Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939021 | 0.95 | CA4 (0.43) | CA4LTA4HDRD2DRD4DRD3 | |
| SCHEMBL8939051 | 0.88 | LTA4H (0.39) | CA4LTA4H | |
| SCHEMBL8939010 | 0.84 | CA1 (0.48) | CA4LTA4HCA12CA1CA2 | |
| SCHEMBL8939012 | 0.83 | DRD2 (0.35) | LTA4HDRD2DRD4DRD3NPC1 | |
| SCHEMBL8938985 | 0.81 | L3MBTL1 (0.43) | CA4LTA4HALDH1A1MAPT | |
| SCHEMBL8939016 | 0.81 | DRD2 (0.36) | LTA4HDRD2DRD4DRD3HTT | |
| SCHEMBL20710748 | 0.81 | CA4 (0.52) | CA4LTA4HDRD2DRD4DRD3 | |
| SCHEMBL8938994 | 0.81 | LTA4H (0.41) | CA4LTA4HDRD2DRD4DRD3 | |
| SCHEMBL8939036 | 0.81 | CYP1A2 (0.35) | LTA4HDRD4KCNH2HTTNPC1 | |
| SCHEMBL8939047 | 0.80 | SCN4A (0.35) | LTA4HDRD2DRD4DRD3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5498741-A | Alkyl aryl arylphosphonites, process for the preparation thereof and use thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-03-12 | — | — | US | disclosed |