Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4458090 | 0.85 | TSHR (0.38) | TSHRTDP1ACHE | |
| SCHEMBL4452080 | 0.85 | TSHR (0.38) | LTA4HTSHRNPC1RAB9ADRD2 | |
| SCHEMBL8939051 | 0.78 | LTA4H (0.39) | LTA4HTSHRTDP1CA4 | |
| SCHEMBL31413770 | 0.77 | TSHR (0.38) | TSHRTDP1ACHE | |
| SCHEMBL7775590 | 0.77 | TSHR (0.38) | TSHRTDP1ACHE | |
| SCHEMBL11704235 | 0.77 | TSHR (0.38) | LTA4HTSHRNPC1RAB9ADRD2 | |
| SCHEMBL11335046 | 0.77 | DRD2 (0.37) | TSHRNPC1HPGDRAB9ADRD2 | |
| SCHEMBL28276666 | 0.75 | TSHR (0.32) | TSHRTDP1ACHE | |
| SCHEMBL14605205 | 0.73 | TSHR (0.33) | LTA4HTSHRTDP1CA4ACHE | |
| SCHEMBL2947384 | 0.72 | ALDH1A1 (0.33) | LTA4HTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5498741-A | Alkyl aryl arylphosphonites, process for the preparation thereof and use thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-03-12 | — | — | US | disclosed |