Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 5/20 | 0.43 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.40 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.40 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.40 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 7/20 | 0.36 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.36 |
| ▸ | POLA1 | P09884 | 1/20 | 0.35 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.34 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939249 | 1.00 | DUT (0.43) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL7788175 | 1.00 | DUT (0.43) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL414704 | 0.86 | DUT (0.51) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL15771583 | 0.86 | DUT (0.51) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL6034458 | 0.80 | DUT (0.53) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL4954183 | 0.80 | DUT (0.53) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL51722 | 0.80 | DUT (0.53) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL1835935 | 0.78 | SLC28A1 (0.55) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL249821 | 0.78 | DUT (0.51) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL10765602 | 0.78 | DUT (0.51) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574149-A | Method of treating HIV infections with 2',3'-dideoxy-3'-fluoro-5-chlorouridine | GLAXO WELLCOME INC. (US) | 1996-11-12 | — | — | US | disclosed |
| EP-0479640-A2 | Novel phosphonate derivatives of certain nucleosides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-04-08 | — | — | EP | disclosed |
| EP-0477454-A1 | Novel phosphonate derivatives of certain nucleosides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-04-01 | — | — | EP | disclosed |