Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 5/20 | 0.67 |
| ▸ | CTSS | P25774 | 3/20 | 0.60 |
| ▸ | CTSK | P43235 | 2/20 | 0.60 |
| ▸ | CTSL | P07711 | 1/20 | 0.60 |
| ▸ | CTSB | P07858 | 1/20 | 0.60 |
| ▸ | CCKBR | P32239 | 6/20 | 0.59 |
| ▸ | ACE | P12821 | 1/20 | 0.55 |
| ▸ | AKT1 | P31749 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7208458 | 1.00 | REN (0.67) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL11050511 | 0.93 | REN (0.75) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL22962389 | 0.93 | REN (0.75) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL27555716 | 0.93 | REN (0.75) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL7860355 | 0.91 | ACE (0.66) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL2173588 | 0.90 | REN (0.67) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL4420859 | 0.90 | REN (0.67) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL7618822 | 0.90 | REN (0.67) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL29484078 | 0.89 | REN (0.68) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL7859364 | 0.88 | KLK5 (0.65) | RENCTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563132-B1 | TETRAPEPTIDE DERIVATIVES AND ANALOGUES | BLACK JAMES FOUNDATION (GB) | 1996-02-07 | — | — | EP | disclosed |
| US-5486597-A | GASTRIN ANTAGONIST AS ANTISECRETORY AGENTS OF GASTRIC JUICE FOR STOMACH CANCER | JAMES BLACK FOUNDATION LIMITED (GB) | 1996-01-23 | — | — | US | disclosed |
| EP-0563132-A1 | TETRAPEPTIDE DERIVATIVES AND ANALOGUES. | BLACK JAMES FOUNDATION (GB) | 1993-10-06 | — | — | EP | disclosed |
| WO-1992011284-A1 | TETRAPEPTIDE DERIVATIVES AND ANALOGUES | THE JAMES BLACK FOUNDATION LIMITED (GB) | 1992-07-09 | — | — | WO | disclosed |