Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 3/20 | 0.67 |
| ▸ | CTSS | P25774 | 7/20 | 0.67 |
| ▸ | CTSK | P43235 | 6/20 | 0.67 |
| ▸ | CTSB | P07858 | 2/20 | 0.67 |
| ▸ | CTSL | P07711 | 1/20 | 0.67 |
| ▸ | ACE | P12821 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | AKT1 | P31749 | 1/20 | 0.58 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.56 |
| ▸ | PPARA | Q07869 | 2/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7618822 | 1.00 | REN (0.67) | RENCTSSCTSKCTSBCTSL | |
| SCHEMBL2173588 | 1.00 | REN (0.67) | RENCTSSCTSKCTSBCTSL | |
| SCHEMBL22962389 | 0.95 | REN (0.75) | RENCTSSCTSKCTSBCTSL | |
| SCHEMBL27555716 | 0.95 | REN (0.75) | RENCTSSCTSKCTSBCTSL | |
| SCHEMBL11050511 | 0.95 | REN (0.75) | RENCTSSCTSKCTSBCTSL | |
| SCHEMBL24438783 | 0.93 | CTSS (0.69) | RENCTSSCTSKCTSBCTSL | |
| SCHEMBL8182259 | 0.93 | CTSS (0.69) | RENCTSSCTSKCTSBCTSL | |
| SCHEMBL13821431 | 0.93 | CTSS (0.69) | RENCTSSCTSKCTSBCTSL | |
| SCHEMBL29484078 | 0.91 | REN (0.68) | RENCTSSCTSKCTSBCTSL | |
| SCHEMBL7208458 | 0.90 | REN (0.67) | RENCTSSCTSKCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357259-A1 | BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-11-09 | — | — | US | disclosed |
| CN-116874515-A | Amino acid-BSH targeted hybrid compound, and preparation method and application thereof | 重庆高硼生物科技有限公司 | 2023-10-13 | — | — | CN | disclosed |
| EP-3897560-B1 | COMPOSITION COMPRISING OXALAMIDE GELATORS AND VEGETABLE OIL | RUDJER BOSKOVIC INST (HR) | 2022-06-29 | — | — | EP | disclosed |
| US-20220023179-A1 | COMPOSITION COMPRISING OXALAMIDE GELATORS AND VEGETABLE OIL | RUDJER BOSKOVIC INSTITUTE (HR) | 2022-01-27 | — | — | US | disclosed |
| US-11207370-B2 | Peptidomimetics for the treatment of coronavirus and picornavirus infections | EMORY UNIVERSITY (US) | 2021-12-28 | — | — | US | disclosed |
| US-20210284655-A1 | LIBRARIES OF HETEROARYL-CONTAINING MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | CYCLENIUM PHARMA INC. (CA) | 2021-09-16 | — | — | US | disclosed |
| US-20210284655-A1 | LIBRARIES OF HETEROARYL-CONTAINING MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | CYCLENIUM PHARMA INC. (CA) | 2021-09-16 | — | — | US | disclosed |
| EP-3327027-B9 | CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF | PFIZER (US) | 2021-07-07 | — | — | EP | disclosed |
| CN-107567438-B | Riluzole prodrugs and uses thereof | 拜尔哈文制药股份有限公司 | 2021-06-29 | — | — | CN | disclosed |
| US-10981931-B2 | Libraries of heteroaryl-containing macrocyclic compounds and methods of making and using the same | CYCLENIUM PHARMA INC. (CA) | 2021-04-20 | — | — | US | disclosed |
| EP-0605667-A1 | DIAMINE DERIVATIVES HAVING SELECTIVE AFFINITY FOR SIGMA RECEPTORS | BATTELLE MEMORIAL INSTITUTE (CH) | 1994-07-13 | — | — | EP | disclosed |
| WO-1993022279-A1 | DIAMINE DERIVATIVES HAVING SELECTIVE AFFINITY FOR SIGMA RECEPTORS | BATTELLE MEMORIAL INSTITUTE (CH) | 1993-11-11 | — | — | WO | disclosed |
| US-5189023-A | Hypotensive agent | AMERICAN CYANAMID COMPANY (US) | 1993-02-23 | — | — | US | disclosed |
| EP-0473936-A1 | Renin Inhibitors | AMERICAN CYANAMID COMPANY (US) | 1992-03-11 | — | — | EP | disclosed |
| US-4997950-A | Antisecretory | MURPHY RICHARD FINBAR (US) | 1991-03-05 | — | — | US | disclosed |
| EP-0376040-A2 | N-phosphinyl di-and tripeptides as renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |
| EP-0071926-B1 | NEW RIBOFURANURONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-08 | — | — | EP | disclosed |
| EP-0190597-A2 | Retro-inverso analogs of the bradykinin potentiating peptide bpp 5a | SCLAVO S.p.A. (IT) | 1986-08-13 | — | — | EP | disclosed |
| US-4479942-A | Tetrahydrofurnancarboxylic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-30 | — | — | US | disclosed |
| EP-0071926-A1 | New ribofuranuronic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-02-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357259-A1 | BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | DOCK11, PAICS, RHOA | REN 4063/4885CTSS 682/4885CTSK 1372/4885 |
| US-20210284655-A1 | LIBRARIES OF HETEROARYL-CONTAINING MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | NCOA3, VDR, GRK3 | REN 3161/4885CTSS 3000/4885CTSK 3034/4885 |
| US-20220023179-A1 | COMPOSITION COMPRISING OXALAMIDE GELATORS AND VEGETABLE OIL | OAT, OTC, ODC1 | REN 2778/4885CTSS 3138/4885CTSK 2499/4885 |
| US-10981931-B2 | Libraries of heteroaryl-containing macrocyclic compounds and methods of making and using the same | NCOA3, VDR, GRK3 | REN 3161/4885CTSS 3000/4885CTSK 3034/4885 |
| US-11207370-B2 | Peptidomimetics for the treatment of coronavirus and picornavirus infections | ACE2, SARS1, VIP | REN 270/4885CTSS 332/4885CTSK 1160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.