Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.34 |
| ▸ | NMUR2 | Q9GZQ4 | 4/20 | 0.34 |
| ▸ | NMUR1 | Q9HB89 | 4/20 | 0.34 |
| ▸ | F2 | P00734 | 3/20 | 0.33 |
| ▸ | XIAP | P98170 | 2/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7509967 | 0.92 | CTSK (0.37) | EPHA2OPRM1OPRK1NMUR2NMUR1 | |
| SCHEMBL2526255 | 0.86 | F2 (0.46) | F2 | |
| SCHEMBL6967946 | 0.85 | F2 (0.38) | EPHA2OPRM1OPRK1NMUR2NMUR1 | |
| SCHEMBL7504596 | 0.85 | F2 (0.45) | F2 | |
| SCHEMBL6976859 | 0.84 | F2 (0.39) | F2 | |
| SCHEMBL7502292 | 0.84 | F2 (0.36) | OPRM1OPRK1NMUR2NMUR1F2 | |
| SCHEMBL8939612 | 0.84 | F2 (0.40) | EPHA2NMUR2NMUR1F2 | |
| SCHEMBL8939663 | 0.83 | F2 (0.39) | F2XIAP | |
| SCHEMBL7506385 | 0.83 | F2 (0.40) | EPHA2NMUR2NMUR1F2 | |
| SCHEMBL7496053 | 0.83 | TP53 (0.39) | OPRM1OPRK1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523308-A | SERINE PROTEASES INHIBITORS; ORAL ANTICOAGULANTS; CHEMICAL INTERMEDIATES; DIPEPTIDES | ORTHO PHARMACEUTICAL CORPORATION | 1996-06-04 | — | — | US | claimed |