Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.50 |
| ▸ | PGR | P06401 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | SHBG | P04278 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10413157 | 0.89 | LMNA (0.70) | LMNAMAPTCYP19A1CYP3A4HIF1A | |
| SCHEMBL11022179 | 0.89 | LMNA (0.73) | LMNAMAPTCYP19A1CYP3A4HIF1A | |
| SCHEMBL10625104 | 0.89 | LMNA (0.73) | LMNAMAPTCYP19A1CYP3A4HIF1A | |
| SCHEMBL8859812 | 0.89 | LMNA (0.73) | LMNAMAPTCYP19A1CYP3A4HIF1A | |
| SCHEMBL3756860 | 0.86 | LMNA (0.69) | LMNAMAPTCYP19A1CYP3A4HSD17B10 | |
| Nitrous Acid SCHEMBL10866222 | 0.85 | LMNA (0.67) | LMNAMAPTCYP19A1CYP3A4HIF1A | |
| SCHEMBL9623217 | 0.85 | HSD17B10 (0.66) | LMNAMAPTCYP19A1CYP3A4HIF1A | |
| Methandrostenolone SCHEMBL4435272 | 0.84 | LMNA (1.00) | LMNAMAPTCYP19A1CYP3A4HIF1A | |
| Methandrostenolone SCHEMBL16755284 | 0.84 | LMNA (1.00) | LMNAMAPTCYP19A1CYP3A4HIF1A | |
| Methandrostenolone SCHEMBL21177905 | 0.84 | LMNA (1.00) | LMNAMAPTCYP19A1CYP3A4HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474701-A | Process for the separation of 4-androsten-3,17-dione and 1,4-androstadien-3,17-dione | VEB JENAPHARM JENA (DD) | 1984-10-02 | — | — | US | claimed |
| JP-8169897-A | — | — | None | — | — | JP | disclosed |
| JP-H08169897-A | NOVEL PRODUCTION OF 16 BETA-METHYL-STEROID AND NOVEL INTERMEDIATE | ROUSSEL UCLAF | 1996-07-02 | — | — | JP | disclosed |
| US-4474701-A | Process for the separation of 4-androsten-3,17-dione and 1,4-androstadien-3,17-dione | VEB JENAPHARM JENA (DD) | 1984-10-02 | — | — | US | disclosed |
| US-4474701-A | Process for the separation of 4-androsten-3,17-dione and 1,4-androstadien-3,17-dione | VEB JENAPHARM JENA (DD) | 1984-10-02 | — | — | US | disclosed |