Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.66 |
| ▸ | PGR | P06401 | 2/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | FNTA | P49354 | 1/20 | 0.49 |
| ▸ | FNTB | P49356 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | IL6 | P05231 | 1/20 | 0.46 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12792409 | 0.86 | HSD17B10 (0.72) | HSD17B10LMNAKMT2AALDH1A1NR3C1 | |
| SCHEMBL8939666 | 0.85 | LMNA (0.73) | HSD17B10LMNAKMT2AALDH1A1NR3C1 | |
| SCHEMBL4545226 | 0.82 | HSD17B10 (0.80) | HSD17B10LMNAKMT2AALDH1A1NR3C1 | |
| SCHEMBL1685744 | 0.82 | HSD17B10 (0.80) | HSD17B10LMNAKMT2AALDH1A1NR3C1 | |
| SCHEMBL13524533 | 0.82 | HSD17B10 (0.80) | HSD17B10LMNAKMT2AALDH1A1NR3C1 | |
| SCHEMBL9623866 | 0.80 | NR3C1 (0.67) | HSD17B10LMNANR3C1PGRHIF1A | |
| SCHEMBL29039130 | 0.80 | HSD17B10 (0.77) | HSD17B10LMNAKMT2AALDH1A1NR3C1 | |
| Prednisone SCHEMBL23974933 | 0.80 | HSD17B10 (1.00) | HSD17B10LMNAKMT2AALDH1A1NR3C1 | |
| Prednisone SCHEMBL20459224 | 0.80 | HSD17B10 (1.00) | HSD17B10LMNAKMT2AALDH1A1NR3C1 | |
| Prednisone SCHEMBL21883168 | 0.80 | HSD17B10 (1.00) | HSD17B10LMNAKMT2AALDH1A1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268400-B1 | STEROIDAL 17ALPHA-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGESTERONES | THE UPJOHN COMPANY (US) | 1992-04-29 | — | — | EP | claimed |