Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | KDM1A | O60341 | 9/20 | 0.52 |
| ▸ | MAOA | P21397 | 5/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.50 |
| ▸ | VCP | P55072 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PHGDH | O43175 | 1/20 | 0.43 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9124456 | 0.77 | RAB9A (0.61) | MEN1KMT2APOLBALOX5AMY1A | |
| SCHEMBL16798757 | 0.73 | KDM1A (0.82) | MEN1KMT2APOLBKDM1AMAOA | |
| SCHEMBL2896407 | 0.71 | NR3C1 (0.62) | MEN1KMT2AALOX5AMY1AVCP | |
| SCHEMBL2762588 | 0.71 | KDM1A (0.87) | MEN1KMT2APOLBKDM1AMAOA | |
| SCHEMBL13109403 | 0.70 | KDM1A (0.76) | MEN1KMT2APOLBKDM1AMAOA | |
| SCHEMBL2762614 | 0.70 | KDM1A (0.69) | MEN1KMT2APOLBKDM1AMAOA | |
| SCHEMBL8939694 | 0.70 | GAA (0.38) | KMT2APOLBALDH1A1GAALMNA | |
| SCHEMBL2900271 | 0.70 | NR3C1 (0.64) | ALOX5AMY1AVCPMAPT | |
| SCHEMBL3455591 | 0.70 | KDM1A (0.75) | MEN1KMT2APOLBKDM1AMAOA | |
| SCHEMBL25069049 | 0.70 | MEN1 (0.64) | MEN1KMT2APOLBKDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626369-B1 | BENZENESULFONAMIDE DERIVATIVE | KYOWA HAKKO KOGYO KK (JP) | 1996-09-18 | — | — | EP | disclosed |
| US-5523464-A | BONE DISORDERS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0626369-A1 | BENZENESULFONAMIDE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-11-30 | — | — | EP | disclosed |