Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521200 | 0.76 | ALDH1A1 (0.52) | GAAALDH1A1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL8939599 | 0.74 | ALDH1A1 (0.45) | GAAALDH1A1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL8939686 | 0.70 | MEN1 (0.53) | GAAALDH1A1KMT2APOLBLMNA | |
| SCHEMBL8939618 | 0.70 | ALDH1A1 (0.44) | GAAALDH1A1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL11351755 | 0.70 | GAA (0.53) | GAAALDH1A1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL8939689 | 0.70 | HPGD (0.53) | GAAALDH1A1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL8939600 | 0.70 | LMNA (0.50) | GAAALDH1A1KMT2ASMN1; SMN2PGR | |
| SCHEMBL8939671 | 0.68 | ALDH1A1 (0.50) | GAAALDH1A1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL8939616 | 0.68 | RECQL (0.55) | GAAALDH1A1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL9413481 | 0.68 | HTR6 (0.39) | GAAALDH1A1KMT2ATDP1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626369-B1 | BENZENESULFONAMIDE DERIVATIVE | KYOWA HAKKO KOGYO KK (JP) | 1996-09-18 | — | — | EP | disclosed |
| US-5523464-A | BONE DISORDERS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |