Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL496697 | 0.91 | TDP1 (0.54) | LMNATDP1FDPSALDH1A1SMN1; SMN2 | |
| SCHEMBL11554275 | 0.89 | LMNA (0.53) | LMNATDP1FDPSSMN1; SMN2L3MBTL1 | |
| SCHEMBL5516006 | 0.77 | KMT2A (0.49) | LMNATDP1FDPSALDH1A1SMN1; SMN2 | |
| SCHEMBL1457801 | 0.76 | L3MBTL1 (0.47) | LMNATDP1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL9600152 | 0.75 | KMT2A (0.50) | LMNATDP1FDPSALDH1A1SMN1; SMN2 | |
| Phenylmethanesulfonic Acid SCHEMBL6115229 | 0.75 | TDP1 (0.50) | LMNATDP1POLBSMN1; SMN2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1500924 | 0.74 | L3MBTL1 (0.46) | LMNATDP1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL497367 | 0.73 | LMNA (0.60) | LMNATDP1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL5432527 | 0.73 | TDP1 (0.47) | LMNATDP1FDPSALDH1A1SMN1; SMN2 | |
| Trifluoromethanesulfonic Acid SCHEMBL2301996 | 0.72 | LMNA (0.44) | LMNATDP1FDPSALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565588-A | 9-alpha-hydroxy steroids, process for their preparation, process for the preparation of the corresponding 9(11)-dehydro derivatives and pharmaceutical preparations containing said steroids | ROUSSEL UCLAF (FR) | 1996-10-15 | — | — | US | claimed |