Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTPRA | P18433 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2593202 | 0.90 | SMN1; SMN2 (0.51) | KMT2AL3MBTL1TDP1LMNASMN1; SMN2 | |
| SCHEMBL8361647 | 0.90 | LMNA (0.49) | KMT2AL3MBTL1TDP1LMNAHRH1 | |
| SCHEMBL5432527 | 0.88 | TDP1 (0.47) | KMT2AL3MBTL1TDP1LMNAHRH1 | |
| SCHEMBL1272066 | 0.88 | L3MBTL1 (0.45) | KMT2AL3MBTL1TDP1LMNAHRH1 | |
| SCHEMBL28641442 | 0.88 | HRH1 (0.52) | KMT2AL3MBTL1TDP1LMNAHRH1 | |
| SCHEMBL14426930 | 0.85 | LMNA (0.45) | KMT2AL3MBTL1TDP1LMNAHRH1 | |
| SCHEMBL5516006 | 0.84 | KMT2A (0.49) | KMT2AL3MBTL1TDP1LMNAHRH1 | |
| SCHEMBL2592540 | 0.84 | KCNA5 (0.55) | KMT2ASMN1; SMN2MAPTPKM | |
| SCHEMBL12139974 | 0.83 | ALDH1A1 (0.45) | KMT2AL3MBTL1TDP1LMNAALDH1A1 | |
| SCHEMBL11773992 | 0.83 | ALDH1A1 (0.42) | KMT2AL3MBTL1TDP1LMNAHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0235111-B1 | INDOLIZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SANOFI S.A. (FR) | 1991-04-10 | — | — | EP | claimed |
| EP-0235111-A1 | Indolizine derivatives, process for their preparation and compositions containing them | SANOFI S.A. (FR) | 1987-09-02 | — | — | EP | claimed |
| CN-115551504-A | Novel pharmacological chaperone compounds of human acid alpha-glucosidase and their therapeutic use | 格勒诺布尔-阿尔卑斯大学 | 2022-12-30 | — | — | CN | disclosed |
| CN-111925308-B | Method for synthesizing N-substituted sulfone diimine by photocatalysis | 广西民族大学 | 2022-03-22 | — | — | CN | disclosed |
| CN-111925308-A | Method for synthesizing N-substituted sulfone diimine by photocatalysis | 广西民族大学 | 2020-11-13 | — | — | CN | disclosed |
| US-5182291-A | Angina pectoris, hypotensive, antiarrhythmia, cerebral vascular insufficiency | SANOFI (FR) | 1993-01-26 | — | — | US | disclosed |
| EP-0235111-B1 | INDOLIZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SANOFI S.A. (FR) | 1991-04-10 | — | — | EP | disclosed |
| EP-0235111-A1 | Indolizine derivatives, process for their preparation and compositions containing them | SANOFI S.A. (FR) | 1987-09-02 | — | — | EP | disclosed |