SCHEMBL8940101

SCHEMBL8940101

O=C(/C=C/C(=O)OCC(O)CO)OCC(O)CO

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.44
KDM4E B2RXH2 1/20 0.44
DUSP3 P51452 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
DGKA P23743 1/20 0.41
FAAH O00519 4/20 0.39
HCAR2 Q8TDS4 3/20 0.37
ATM Q13315 1/20 0.37
ALDH1A1 P00352 2/20 0.36
TSHR P16473 1/20 0.35
USP2 O75604 2/20 0.32
CYP3A4 P08684 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4439685 1.00 LMNA (0.44) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL6665040 1.00 LMNA (0.44) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL17172093 0.94 LMNA (0.41) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL4439683 0.92 HCAR2 (0.50) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL8940099 0.92 HCAR2 (0.50) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL8661906 0.92 HCAR2 (0.50) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL16994445 0.90 HCAR2 (0.50) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL17048417 0.90 HCAR2 (0.50) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL17048229 0.90 HCAR2 (0.50) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL17048270 0.90 HCAR2 (0.50) LMNAKDM4EDUSP3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119235804-A Carbamazepine pharmaceutical composition and preparation method and application thereof 上海则正医药科技股份有限公司 2025-01-03 CN claimed
US-20240238206-A1 LOSARTAN-CONTAINING MICRO TABLET FOR PEDIATRIC APPLICATIONS Midas Pharma GmbH (DE) 2024-07-18 US claimed
CN-118055759-A Miniature tablet containing losartan for pediatric use 米达斯制药有限责任公司 2024-05-17 CN claimed
EP-4135668-B1 SOLID ORAL DOSAGE FORM COMPRISING POMALIDOMIDE TECNIMEDE SOCIEDADE TECNICO MEDICINAL SA (PT) 2024-04-17 EP claimed
EP-4333816-A1 LOSARTAN-CONTAINING MICRO TABLET FOR PEDIATRIC APPLICATIONS Midas Pharma GmbH (DE) 2024-03-13 EP claimed
CN-116947642-A Long-residence polyalcohol hair care raw material molecule and preparation and application thereof 江南大学 2023-10-27 CN claimed
WO-2023031755-A1 FORMULATIONS, COMPOSITIONS AND METHODS FOR THE DELIVERY OF NEURODEGENERATIVE DRUGS THEREOF AVACA PHARMA PRIVATE LIMITED (IN) 2023-03-09 WO claimed
EP-4135668-A1 SOLID ORAL DOSAGE FORM COMPRISING POMALIDOMIDE Tecnimede, Sociedade Técnico-Medicinal, SA (PT) 2023-02-22 EP claimed
WO-2023002338-A1 COMPOSITIONS, METHODS OF MAKING AND USING SAME FOR THE DELIVERY OF ULCEROGENIC DRUGS THEREOF AVACA PHARMA PRIVATE LIMITED (IN) 2023-01-26 WO claimed
WO-2022234139-A1 LOSARTAN-CONTAINING MICRO TABLET FOR PEDIATRIC APPLICATIONS Midas Pharma GmbH (DE) 2022-11-10 WO claimed
EP-3135275-B1 PHARMACEUTICAL COMPOSITION CAPABLE OF THE INCORPORATION OF LENALIDOMIDE IN VARIOUS CRYSTALLINE MODIFICATIONS GRINDEKS JSC (LV) 2020-05-13 EP claimed
WO-2019185862-A1 ORAL DOSAGE FORMS COMPRISING POMALIDOMIDE CRYSTALLINE FORM A Midas Pharma GmbH (DE) 2019-10-03 WO claimed
EP-3545949-A1 ORAL DOSAGE FORMS COMPRISING POMALIDOMIDE CRYSTALLINE FORM A Midas Pharma GmbH (DE) 2019-10-02 EP claimed
US-20180243283-A1 PHARMACEUTICAL COMPOSITION CAPABLE OF THE INCORPORATION OF LENALIDOMIDE IN VARIOUS CRYSTALLINE MODIFICATIONS GRINDEKS, A JOINT STOCK COMPANY (LV) 2018-08-30 US claimed
US-9895325-B2 Tablet composition comprising cinacalcet hydrochloride SYNTHON B.V. (NL) 2018-02-20 US claimed
WO-2017032870-A1 PHARMACEUTICAL COMPOSITION CAPABLE OF THE INCORPORATION OF LENALIDOMIDE IN VARIOUS CRYSTALLINE MODIFICATIONS GRINDEKS, A JOINT STOCK COMPANY (LV) 2017-03-02 WO claimed
EP-3135275-A1 PHARMACEUTICAL COMPOSITION CAPABLE OF THE INCORPORATION OF LENALIDOMIDE IN VARIOUS CRYSTALLINE MODIFICATIONS Grindeks, A Joint Stock Company (LV) 2017-03-01 EP claimed
EP-3002006-A1 Pharmaceutical composition capable for the incorporation Febuxostat in the crystalline modifications F10, II, G and A Bluepharma - Industria Farmacêutica, S.A. (PT) 2016-04-06 EP claimed
WO-2014029953-A1 HOT MELT EXTRUDED (HME) PHARMACEUTICAL COMPOSITION OF CINACALCET CIPLA LIMITED (IN) 2014-02-27 WO claimed
EP-0516141-B1 Pharmaceutical controlled-release composition with bioadhesive properties RECORDATI CHEM PHARM (CH) 1996-08-14 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180243283-A1 PHARMACEUTICAL COMPOSITION CAPABLE OF THE INCORPORATION OF LENALIDOMIDE IN VARIOUS CRYSTALLINE MODIFICATIONS RPL7, RPL26, PDCD2L LMNA 1569/4885KDM4E 1761/4885DUSP3 424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.