Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 17/20 | 0.67 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8999931 | 0.80 | CYP19A1 (0.67) | CYP19A1NR3C1CYP17A1 | |
| SCHEMBL1421773 | 0.80 | CYP19A1 (1.00) | CYP19A1NR3C1 | |
| SCHEMBL14284877 | 0.80 | CYP19A1 (1.00) | CYP19A1NR3C1 | |
| SCHEMBL10625133 | 0.80 | CYP19A1 (1.00) | CYP19A1NR3C1 | |
| SCHEMBL8768647 | 0.79 | CYP19A1 (0.40) | CYP19A1NR3C1CYP17A1 | |
| SCHEMBL9073294 | 0.78 | CYP19A1 (0.63) | CYP19A1NR3C1CYP17A1 | |
| SCHEMBL10708164 | 0.77 | CYP19A1 (0.62) | CYP19A1NR3C1CYP17A1 | |
| SCHEMBL10625100 | 0.76 | CYP19A1 (0.71) | CYP19A1NR3C1CYP17A1 | |
| SCHEMBL8999928 | 0.76 | CYP19A1 (0.74) | CYP19A1NR3C1 | |
| SCHEMBL10625095 | 0.76 | CYP19A1 (0.71) | CYP19A1NR3C1CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565588-A | 9-alpha-hydroxy steroids, process for their preparation, process for the preparation of the corresponding 9(11)-dehydro derivatives and pharmaceutical preparations containing said steroids | ROUSSEL UCLAF (FR) | 1996-10-15 | — | — | US | disclosed |
| US-5352809-A | 9-alpha-hydroxy steroids, process for their preparation, process for the preparation of the corresponding 9(11)-dehydro derivatives and pharmaceutical preparations containing such steroids | GIST-BROCADES N.V. (NL) | 1994-10-04 | — | — | US | disclosed |
| EP-0263569-B1 | 9-alpha-hydroxysteroids, process for their preparation and process for the preparation of the corresponding 9(11)-dehydro-derivatives. | ROUSSEL-UCLAF (FR) | 1992-12-09 | — | — | EP | disclosed |
| EP-0263569-A2 | 9-alpha-hydroxysteroids, process for their preparation and process for the preparation of the corresponding 9(11)-dehydro-derivatives. | ROUSSEL-UCLAF (FR) | 1988-04-13 | — | — | EP | disclosed |