Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8940108 | 0.79 | CYP19A1 (0.67) | CYP19A1CYP17A1NR3C1 | |
| SCHEMBL8939564 | 0.75 | NR3C1 (0.40) | CYP19A1CYP17A1SRD5A2ARSRD5A1 | |
| SCHEMBL8769318 | 0.74 | CYP19A1 (0.40) | CYP19A1CYP17A1SRD5A2ARSRD5A1 | |
| SCHEMBL5479291 | 0.62 | G6PD (0.58) | CYP19A1CYP17A1SRD5A2 | |
| SCHEMBL14565708 | 0.62 | G6PD (0.58) | CYP19A1CYP17A1SRD5A2 | |
| SCHEMBL11778305 | 0.60 | POLB (0.59) | CYP19A1 | |
| SCHEMBL8999931 | 0.59 | CYP19A1 (0.67) | CYP19A1CYP17A1NR3C1 | |
| SCHEMBL8768653 | 0.59 | POLB (0.42) | CYP19A1CYP17A1 | |
| SCHEMBL16172301 | 0.58 | CYP17A1 (0.56) | CYP19A1CYP17A1SRD5A2ARSRD5A1 | |
| SCHEMBL14568519 | 0.58 | CYP19A1 (0.57) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685487-B1 | A new method of preparation of a 16-beta-steroid and new intermediates of said preparation | ROUSSEL UCLAF (FR) | 1997-09-03 | — | — | EP | disclosed |
| EP-0685487-A1 | A new method of preparation of a 16-beta-steroid and new intermediates of said preparation | ROUSSEL-UCLAF (FR) | 1995-12-06 | — | — | EP | disclosed |