Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 3/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4355726 | 0.90 | LMNA (0.52) | LMNAMEN1MAPTKMT2ARAB9A | |
| SCHEMBL11337607 | 0.84 | LMNA (0.70) | LMNAMEN1MAPTKMT2ARAB9A | |
| SCHEMBL11347034 | 0.84 | CNR1 (0.61) | LMNAMEN1KMT2ACNR1 | |
| SCHEMBL3461364 | 0.81 | LMNA (0.72) | LMNACNR1CNR2ALDH1A1TSHR | |
| SCHEMBL2847688 | 0.76 | BLM (0.47) | ALDH1A1HTTNPSR1TYRTSHR | |
| SCHEMBL11747540 | 0.75 | LMNA (0.49) | LMNAMEN1MAPTKMT2ARAB9A | |
| SCHEMBL27676416 | 0.73 | HTT (0.44) | MEN1MAPTKMT2AALDH1A1HTT | |
| SCHEMBL27676419 | 0.73 | HTT (0.44) | MEN1MAPTKMT2AALDH1A1HTT | |
| SCHEMBL21232816 | 0.72 | ALDH1A1 (0.45) | LMNAMAPTALDH1A1TP53TYR | |
| SCHEMBL11334858 | 0.71 | KDM1A (0.51) | LMNAMEN1MAPTKMT2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5567411-A | ADMINISTERING TO A WARM-BLOODED ANIMAL TO OBTAIN A MAGNETIC RESONANCE IMAGE OF SUBJECT | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF OREGON (US) | 1996-10-22 | — | — | US | disclosed |