Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4355726 | 0.89 | LMNA (0.52) | LMNAALDH1A1MEN1KMT2ACNR1 | |
| SCHEMBL8940197 | 0.84 | LMNA (0.49) | LMNAALDH1A1MEN1KMT2ACNR1 | |
| SCHEMBL22408310 | 0.82 | LMNA (1.00) | LMNAALDH1A1SLC6A9MEN1KMT2A | |
| SCHEMBL11347034 | 0.82 | CNR1 (0.61) | LMNASLC6A9MEN1KMT2AHSD17B2 | |
| Hydrochloric Acid SCHEMBL28055613 | 0.81 | LMNA (0.97) | LMNAALDH1A1SLC6A9MEN1KMT2A | |
| SCHEMBL14409534 | 0.76 | LMNA (0.72) | LMNAALDH1A1SLC6A9MEN1KMT2A | |
| SCHEMBL9980569 | 0.75 | LMNA (0.59) | LMNAALDH1A1SLC6A9MEN1KMT2A | |
| SCHEMBL10138758 | 0.75 | LMNA (0.69) | LMNAALDH1A1SLC6A9MEN1KMT2A | |
| SCHEMBL2010681 | 0.75 | LMNA (0.69) | LMNAALDH1A1SLC6A9MEN1KMT2A | |
| SCHEMBL12604986 | 0.75 | LMNA (0.69) | LMNAALDH1A1SLC6A9MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000952-B1 | BENZHYDRYL GUANIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS | McNeilab, Inc. (US) | 1981-02-11 | — | — | EP | disclosed |
| US-4161541-A | HYPOGLYCEMIC AGENTS | MCNEIL LABORATORIES, INC. (US) | 1979-07-17 | — | — | US | disclosed |
| EP-0000952-A1 | Benzhydryl guanidine derivatives and pharmaceutical compositions | McNeilab, Inc. (US) | 1979-03-07 | — | — | EP | disclosed |
| US-4101659-A | LOWERING BLOOD SUGAR | MCNEIL LABORATORIES, INCORPORATED (US) | 1978-07-18 | — | — | US | disclosed |