Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 6/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.59 |
| ▸ | AR | P10275 | 4/20 | 0.54 |
| ▸ | PGR | P06401 | 4/20 | 0.54 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.54 |
| ▸ | SHBG | P04278 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9623805 | 1.00 | NR3C1 (0.60) | NR3C1CYP19A1ARPGRNR3C2 | |
| SCHEMBL10413728 | 0.90 | NR3C1 (0.58) | NR3C1CYP19A1ARPGRNR3C2 | |
| SCHEMBL10629758 | 0.89 | NR3C1 (0.60) | NR3C1CYP19A1ARPGRNR3C2 | |
| SCHEMBL10781341 | 0.89 | NR3C1 (0.60) | NR3C1CYP19A1ARPGRNR3C2 | |
| SCHEMBL29534861 | 0.85 | NR3C1 (0.66) | NR3C1CYP19A1ARPGRNR3C2 | |
| SCHEMBL10390166 | 0.85 | NR3C1 (0.66) | NR3C1CYP19A1ARPGRNR3C2 | |
| SCHEMBL9623872 | 0.84 | NR3C1 (0.45) | NR3C1CYP19A1ARPGRNR3C2 | |
| SCHEMBL9624281 | 0.83 | NR3C1 (0.43) | NR3C1CYP19A1ARPGRNR3C2 | |
| SCHEMBL17775786 | 0.83 | CYP19A1 (0.68) | NR3C1CYP19A1ARPGRNR3C2 | |
| SCHEMBL9622893 | 0.83 | NR3C1 (0.41) | NR3C1CYP19A1ARPGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268400-B1 | STEROIDAL 17ALPHA-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGESTERONES | THE UPJOHN COMPANY (US) | 1992-04-29 | — | — | EP | claimed |
| JP-57062300-A | — | — | None | — | — | JP | disclosed |
| JP-57062296-A | — | — | None | — | — | JP | disclosed |
| JP-6056882-A | — | — | None | — | — | JP | disclosed |
| US-5565588-A | 9-alpha-hydroxy steroids, process for their preparation, process for the preparation of the corresponding 9(11)-dehydro derivatives and pharmaceutical preparations containing said steroids | ROUSSEL UCLAF (FR) | 1996-10-15 | — | — | US | disclosed |
| US-5352809-A | 9-alpha-hydroxy steroids, process for their preparation, process for the preparation of the corresponding 9(11)-dehydro derivatives and pharmaceutical preparations containing such steroids | GIST-BROCADES N.V. (NL) | 1994-10-04 | — | — | US | disclosed |
| JP-H0656882-A | NEW PREPARATION OF DELTA9(11)-STEROID COMPOUND | ROUSSEL UCLAF | 1994-03-01 | — | — | JP | disclosed |
| EP-0263569-B1 | 9-alpha-hydroxysteroids, process for their preparation and process for the preparation of the corresponding 9(11)-dehydro-derivatives. | ROUSSEL-UCLAF (FR) | 1992-12-09 | — | — | EP | disclosed |
| EP-0268400-B1 | STEROIDAL 17ALPHA-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGESTERONES | THE UPJOHN COMPANY (US) | 1992-04-29 | — | — | EP | disclosed |
| EP-0153001-B1 | STEROIDS HAVING AN ENAMIDE OR ENIMIDE GROUP AND THEIR PREPARATION | THE UPJOHN COMPANY (US) | 1992-03-11 | — | — | EP | disclosed |
| US-4921638-A | 17β-cyano-9α,17α-dihydroxyandrost-4-en-3-one | THE UPJOHN COMPANY (US) | 1990-05-01 | — | — | US | disclosed |
| US-4831131-A | 11β,17α-Dihydroxy-17β-cyano-androstanes | THE UPJOHN COMPANY (US) | 1989-05-16 | — | — | US | disclosed |
| EP-0268400-A1 | Steroidal 17alpha-silyl ethers and process to corticoids and progesterones | THE UPJOHN COMPANY (US) | 1988-05-25 | — | — | EP | disclosed |
| EP-0263569-A2 | 9-alpha-hydroxysteroids, process for their preparation and process for the preparation of the corresponding 9(11)-dehydro-derivatives. | ROUSSEL-UCLAF (FR) | 1988-04-13 | — | — | EP | disclosed |
| US-4585590-A | Cyanohydrin process | THE UPJOHN COMPANY (US) | 1986-04-29 | — | — | US | disclosed |
| US-4548748-A | Cyanohydrin process | THE UPJOHN COMPANY (US) | 1985-10-22 | — | — | US | disclosed |
| EP-0153001-A2 | Steroids having an enamide or enimide group and their preparation | THE UPJOHN COMPANY (US) | 1985-08-28 | — | — | EP | disclosed |
| US-4500461-A | Cyanohydrin process | THE UPJOHN COMPANY (US) | 1985-02-19 | — | — | US | disclosed |
| JP-S5762296-A | PREPARATION OF 17ALPHA-HYDROXYPROGESTERONE DERIVATIVE | MITSUBISHI CHEM IND LTD | 1982-04-15 | — | — | JP | disclosed |
| JP-S5762300-A | 17ALPHA-CYANOSTEROID | MITSUBISHI CHEM IND LTD | 1982-04-15 | — | — | JP | disclosed |