Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 6/20 | 0.45 |
| ▸ | AR | P10275 | 3/20 | 0.42 |
| ▸ | PGR | P06401 | 2/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9623805 | 0.84 | NR3C1 (0.60) | NR3C1ARPGRNR3C2CYP19A1 | |
| SCHEMBL8940232 | 0.84 | NR3C1 (0.60) | NR3C1ARPGRNR3C2CYP19A1 | |
| SCHEMBL10582213 | 0.81 | NR3C1 (0.41) | NR3C1ARPGRNR3C2CYP19A1 | |
| SCHEMBL9623669 | 0.77 | NFKB1 (0.56) | NR3C1ARPGRNR3C2CYP19A1 | |
| SCHEMBL9623603 | 0.75 | ABCB11 (0.38) | NR3C1ARPGRNR3C2CYP19A1 | |
| SCHEMBL10413728 | 0.74 | NR3C1 (0.58) | NR3C1ARPGRNR3C2CYP19A1 | |
| SCHEMBL10629758 | 0.73 | NR3C1 (0.60) | NR3C1ARPGRNR3C2CYP19A1 | |
| SCHEMBL10781341 | 0.73 | NR3C1 (0.60) | NR3C1ARPGRNR3C2CYP19A1 | |
| SCHEMBL9623997 | 0.73 | ABCB11 (0.36) | NR3C1ARPGRNR3C2CYP19A1 | |
| SCHEMBL8939564 | 0.72 | NR3C1 (0.40) | NR3C1ARPGRNR3C2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268400-B1 | STEROIDAL 17ALPHA-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGESTERONES | THE UPJOHN COMPANY (US) | 1992-04-29 | — | — | EP | claimed |