Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoylphenylurea SCHEMBL83109 | 0.84 | L3MBTL1 (0.48) | KMT2ARAB9AGAAPOLBLMNA | |
| Benzoylphenylurea SCHEMBL31707309 | 0.83 | TDP1 (0.46) | KMT2ARAB9AGAAPOLBNPC1 | |
| SCHEMBL10963216 | 0.81 | PBRM1 (0.55) | PBRM1F2PLGPRSS1PRSS2 | |
| SCHEMBL2129928 | 0.80 | PBRM1 (0.58) | PBRM1F2PLGPRSS1PRSS2 | |
| SCHEMBL6324478 | 0.79 | MAOA (0.59) | PBRM1KMT2ARAB9APOLBNPC1 | |
| SCHEMBL8940246 | 0.79 | PBRM1 (0.56) | PBRM1F2PLGPRSS1PRSS2 | |
| SCHEMBL13723635 | 0.75 | PBRM1 (0.51) | PBRM1F2PLGPRSS1PRSS2 | |
| SCHEMBL764342 | 0.74 | NPSR1 (0.50) | KMT2ARAB9AMEN1POLBNPC1 | |
| SCHEMBL4837185 | 0.73 | CES2 (0.48) | KMT2ARAB9AMEN1POLBNPC1 | |
| SCHEMBL5032653 | 0.73 | CES2 (0.48) | KMT2ARAB9AMEN1POLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320448-B1 | 3-Aminobenzoyl phenyl urea | CIBA GEIGY AG (CH) | 1994-12-28 | — | — | EP | disclosed |
| US-4946854-A | PESTICIDES | CIBA-GEIGY CORPORATION (US) | 1990-08-07 | — | — | US | disclosed |
| US-4946854-A | PESTICIDES | CIBA-GEIGY CORPORATION (US) | 1990-08-07 | — | — | US | disclosed |
| EP-0320448-A2 | 3-Aminobenzoyl phenyl urea | CIBA-GEIGY AG (CH) | 1989-06-14 | — | — | EP | disclosed |