Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | VDR | P11473 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30380565 | 1.00 | ALDH1A1 (0.43) | ALDH1A1CA12CA1CA9C5AR1 | |
| SCHEMBL8940473 | 1.00 | ALDH1A1 (0.43) | ALDH1A1CA12CA1CA9C5AR1 | |
| SCHEMBL863528 | 0.98 | CA12 (0.42) | ALDH1A1CA12CA1CA9C5AR1 | |
| SCHEMBL8875958 | 0.90 | CYP24A1 (0.39) | ALDH1A1CA12CA1CA9C5AR1 | |
| SCHEMBL8672969 | 0.88 | CYP24A1 (0.39) | ALDH1A1CA12CA1CA9C5AR1 | |
| SCHEMBL26541640 | 0.88 | ALDH1A1 (0.43) | ALDH1A1CA12CA1CA9C5AR1 | |
| SCHEMBL13913110 | 0.88 | ALDH1A1 (0.43) | ALDH1A1CA12CA1CA9C5AR1 | |
| SCHEMBL18613994 | 0.87 | ALDH1A1 (0.53) | ALDH1A1CA12CA1CA9STAT3 | |
| SCHEMBL478342 | 0.87 | ALDH1A1 (0.53) | ALDH1A1CA12CA1CA9STAT3 | |
| SCHEMBL18644929 | 0.87 | ALDH1A1 (0.53) | ALDH1A1CA12CA1CA9STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250032623-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND THEIR USE IN TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. | 2025-01-30 | — | — | US | disclosed |
| WO-2023059583-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND THEIR USE IN TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2023-04-13 | — | — | WO | disclosed |
| US-20230098438-A1 | OXAZINE-BASED WATER-SOLUBLE FLUOROPHORE COMPOUNDS FOR IN VIVO NERVE IMAGING | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2023-03-30 | — | — | US | disclosed |
| US-20230098686-A1 | NERVE SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | UNIV OREGON HEALTH & SCIENCE (US) | 2023-03-30 | — | — | US | disclosed |
| EP-4084829-A1 | OXAZINE-BASED WATER-SOLUBLE FLUOROPHORE COMPOUNDS FOR IN VIVO NERVE IMAGING | Oregon Health & Science University (US) | 2022-11-09 | — | — | EP | disclosed |
| WO-2021158820-A1 | NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-08-12 | — | — | WO | disclosed |
| WO-2021138116-A1 | OXAZINE-BASED WATER-SOLUBLE FLUOROPHORE COMPOUNDS FOR IN VIVO NERVE IMAGING | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-07-08 | — | — | WO | disclosed |
| US-8354147-B2 | Polymerizable liquid crystal compound, composition and polymer | JNC CORPORATION (JP) | 2013-01-15 | — | — | US | disclosed |
| US-20110001088-A1 | Polymerizable Liquid Crystal Compound, Composition and Polymer | CHISSO CORPORATION (JP) | 2011-01-06 | — | — | US | disclosed |
| US-5563230-A | POLYETHERSILOXANES | NATIONAL SCIENCE COUNCIL (TW) | 1996-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110001088-A1 | Polymerizable Liquid Crystal Compound, Composition and Polymer | CCNT1, H1-0, CCNA1 | ALDH1A1 1447/4885CA12 523/4885CA1 112/4885 |
| US-20230098438-A1 | OXAZINE-BASED WATER-SOLUBLE FLUOROPHORE COMPOUNDS FOR IN VIVO NERVE IMAGING | GAP43, NTRK1, MAG | ALDH1A1 861/4885CA12 2344/4885CA1 1882/4885 |
| US-20230098686-A1 | NERVE SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | PFAS, NPFFR2, NPFFR1 | ALDH1A1 556/4885CA12 2687/4885CA1 3277/4885 |
| US-20250032623-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND THEIR USE IN TREATING DISEASE | AURKB, CDK9, AURKA | ALDH1A1 4001/4885CA12 3122/4885CA1 3345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.