Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8940404 | 0.85 | MEN1 (0.37) | — | |
| SCHEMBL8940472 | 0.82 | ROCK2 (0.35) | ROCK2 | |
| SCHEMBL3522319 | 0.82 | THRB (0.32) | — | |
| SCHEMBL605278 | 0.74 | — | — | |
| SCHEMBL8940412 | 0.74 | — | — | |
| SCHEMBL2499893 | 0.73 | ALDH1A1 (0.42) | — | |
| SCHEMBL9019108 | 0.73 | ALDH1A1 (0.42) | — | |
| SCHEMBL5013566 | 0.73 | THRB (0.35) | — | |
| SCHEMBL5433812 | 0.73 | — | — | |
| SCHEMBL27698012 | 0.72 | THRB (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504240-A | HYDROBORATION AND REDUCING AGENTS | ALDRICH CHEMICAL COMPANY, INC. (US) | 1996-04-02 | — | — | US | disclosed |