Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18057577 | 0.89 | PTGDR2 (0.50) | SMN1; SMN2MAPTSLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL14439661 | 0.88 | ALDH1A1 (0.48) | P2RX1SMN1; SMN2MAPTRAB9AMAOB | |
| SCHEMBL27448009 | 0.87 | MAOA (0.47) | SMN1; SMN2MAPTRAB9ASLC6A4SLC6A3 | |
| SCHEMBL27365815 | 0.87 | SMN1; SMN2 (0.49) | P2RX1SMN1; SMN2RAB9APOLBNPC1 | |
| SCHEMBL10886306 | 0.86 | SLC6A4 (0.50) | P2RX1SMN1; SMN2MAPTRAB9ASLC6A4 | |
| SCHEMBL5631648 | 0.83 | MAPT (0.55) | SMN1; SMN2MAPTRAB9ASLC6A4SLC6A3 | |
| SCHEMBL809394 | 0.82 | ALDH1A1 (0.59) | SMN1; SMN2MAPTRAB9AALDH1A1TP53 | |
| SCHEMBL15276750 | 0.82 | HSD17B3 (0.44) | SMN1; SMN2MAPTRAB9ASLC6A4SLC6A3 | |
| SCHEMBL20117002 | 0.81 | ALDH1A1 (0.50) | P2RX1SMN1; SMN2MAPTMAOBMAOA | |
| SCHEMBL2558658 | 0.81 | AKR1C3 (0.51) | SMN1; SMN2MAPTRAB9AALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8048647-A | — | — | None | — | — | JP | disclosed |
| JP-H0848647-A | PRODUCTION OF INDANONE DERIVATIVE | SUMITOMO CHEM CO LTD | 1996-02-20 | — | — | JP | disclosed |
| US-4168315-A | ANTICOAGULANTS | THE UPJOHN COMPANY (US) | 1979-09-18 | — | — | US | disclosed |