Methacrylic Acid

Methacrylic Acid

SCHEMBL8940713

C=C(C)C(=O)O.C=C(C)C(=O)O.C=C(C)C(=O)O.C=CCOC(=O)C(=C)C.CCC(CO)(CO)CO

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.37
TSHR P16473 4/20 0.36
ALDH1A1 P00352 2/20 0.34
TP53 P04637 1/20 0.34
CYP3A4 P08684 1/20 0.34
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HIF1A Q16665 1/20 0.34
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15303703 0.95 THRB (0.40) THRBTSHRALDH1A1TP53CYP3A4
SCHEMBL15303620 0.87 TSHR (0.41) THRBTSHRALDH1A1TP53CYP3A4
Methacrylic Acid SCHEMBL1637663 0.86 THRB (0.35) THRBTSHRALDH1A1TP53CYP3A4
Methacrylic Acid SCHEMBL2701657 0.86 THRB (0.35) THRBTSHRALDH1A1TP53CYP3A4
SCHEMBL11320353 0.85 CYP3A4 (0.41) THRBTSHRALDH1A1TP53CYP3A4
SCHEMBL16399244 0.85 THRB (0.40) THRBTSHRALDH1A1TP53CYP3A4
Methacrylic Acid SCHEMBL655219 0.85 TSHR (0.45) THRBTSHRALDH1A1TP53CYP3A4
Methacrylic Acid SCHEMBL250051 0.85 TSHR (0.45) THRBTSHRALDH1A1TP53CYP3A4
Methacrylic Acid SCHEMBL28243084 0.84 TSHR (0.41) THRBTSHRALDH1A1TP53CYP3A4
Methacrylic Acid SCHEMBL11017971 0.84 TSHR (0.44) THRBTSHRALDH1A1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0716669-A1 LOW DENSITY POROUS CROSSLINKED POLYMERIC MATERIALS SHELL OIL CO (US) 1996-06-19 EP claimed
WO-1995006681-A1 LOW DENSITY POROUS CROSSLINKED POLYMERIC MATERIALS SHELL OIL COMPANY (US) 1995-03-09 WO claimed
US-5340842-A An addition copolymer consisting of at least one saccharide fatty acid ester as cell control foaming agent; stability, high adsorption; adsorbers/materials/, diapers, wipes SHELL OIL COMPANY (US) 1994-08-23 US claimed