Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.51 |
| ▸ | MMP9 | P14780 | 3/20 | 0.51 |
| ▸ | MMP8 | P22894 | 3/20 | 0.51 |
| ▸ | MMP12 | P39900 | 3/20 | 0.51 |
| ▸ | MMP13 | P45452 | 3/20 | 0.51 |
| ▸ | MMP14 | P50281 | 3/20 | 0.51 |
| ▸ | MMP16 | P51512 | 3/20 | 0.51 |
| ▸ | MMP1 | P03956 | 2/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | MMP3 | P08254 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9379437 | 0.90 | HSD11B1 (0.54) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL27718757 | 0.83 | GABRA1 (0.55) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL9962272 | 0.82 | HSD11B1 (0.60) | MMP2MMP9MMP8MMP12MMP13 | |
| Benzene SCHEMBL27770108 | 0.80 | HSD11B1 (0.46) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL24498677 | 0.79 | HSD11B1 (0.47) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL9059771 | 0.79 | MMP2 (0.47) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL26505599 | 0.78 | HSD11B1 (0.46) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL29353004 | 0.78 | HSD11B1 (0.47) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL22927502 | 0.78 | HSD11B1 (0.47) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL29617 | 0.78 | HSD11B1 (0.47) | MMP2MMP9MMP8MMP12MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565470-A | HYPOTENSIVE OR ANTIARRHYTHMIA AGENTS, ALSO FOR TREATMENT OF ANGINA OR GLAUCOMA | SANOFI (FR) | 1996-10-15 | — | — | US | disclosed |
| US-5340820-A | Useful for treatment of ocular diseases, angina pectoris, hypertension and arrhythmia | ELF SANOFI (FR) | 1994-08-23 | — | — | US | disclosed |