Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.34 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.34 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.34 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8029414 | 0.74 | TSHR (0.42) | TP53TSHRPRKCAALDH1A1CTSK | |
| SCHEMBL8941175 | 0.73 | ALDH1A1 (0.41) | TSHRPRKCAALDH1A1KMT2APOLB | |
| SCHEMBL8941400 | 0.73 | ALDH1A1 (0.41) | TSHRPRKCAALDH1A1KMT2APOLB | |
| SCHEMBL9299208 | 0.69 | MEN1 (0.36) | TP53TSHRPRKCACTSKNPC1 | |
| SCHEMBL26093507 | 0.65 | TSHR (0.61) | TP53TSHRALDH1A1NPC1MEN1 | |
| SCHEMBL12650544 | 0.63 | ALDH1A1 (0.44) | TP53TSHRPRKCAALDH1A1CTSK | |
| SCHEMBL13296338 | 0.62 | TSHR (0.41) | TP53TSHRPRKCAALDH1A1NPC1 | |
| SCHEMBL8327066 | 0.62 | LGALS9 (0.42) | TP53TSHRPRKCAALDH1A1CTSK | |
| 1,4-Butanediol SCHEMBL28033966 | 0.62 | TSHR (0.51) | TP53TSHRPRKCAALDH1A1NPC1 | |
| SCHEMBL872053 | 0.61 | TSHR (0.59) | TP53TSHRPRKCAALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707590-A1 | DIDEOXYFRUCTONUCLEOTIDES AND DEOXYFRUCTONUCLEOTIDES AS DNA POLYMERASE SUBSTRATES | DU PONT (US) | 1996-04-24 | — | — | EP | disclosed |
| WO-1995001986-A1 | DIDEOXYFRUCTONUCLEOTIDES AND DEOXYFRUCTONUCLEOTIDES AS DNA POLYMERASE SUBSTRATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-01-19 | — | — | WO | disclosed |