Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 3/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941175 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TDP1MAPK1HIF1ASLC6A2 | |
| SCHEMBL8941179 | 0.73 | TP53 (0.37) | ALDH1A1SLC6A2SLC6A3KMT2APRKCA | |
| SCHEMBL7214561 | 0.68 | ALDH1A1 (0.39) | ALDH1A1TDP1MAPK1HIF1ASLC6A2 | |
| SCHEMBL8029410 | 0.68 | LGALS9 (0.40) | ALDH1A1TDP1MAPK1HIF1AKMT2A | |
| SCHEMBL9027528 | 0.68 | LGALS9 (0.40) | ALDH1A1TDP1MAPK1HIF1AKMT2A | |
| SCHEMBL31120392 | 0.66 | ALDH1A1 (0.45) | ALDH1A1TDP1KMT2APRKCAADRB2 | |
| SCHEMBL17860796 | 0.66 | ALDH1A1 (0.41) | ALDH1A1TDP1MAPK1HIF1ASLC6A2 | |
| SCHEMBL38654945 | 0.65 | LMNA (0.49) | ALDH1A1TDP1MAPK1HIF1ASLC6A2 | |
| SCHEMBL6099706 | 0.64 | LMNA (0.42) | ALDH1A1TDP1MAPK1HIF1ASLC6A2 | |
| SCHEMBL6099711 | 0.64 | LMNA (0.42) | ALDH1A1TDP1MAPK1HIF1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707590-A1 | DIDEOXYFRUCTONUCLEOTIDES AND DEOXYFRUCTONUCLEOTIDES AS DNA POLYMERASE SUBSTRATES | DU PONT (US) | 1996-04-24 | — | — | EP | disclosed |
| WO-1995001986-A1 | DIDEOXYFRUCTONUCLEOTIDES AND DEOXYFRUCTONUCLEOTIDES AS DNA POLYMERASE SUBSTRATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-01-19 | — | — | WO | disclosed |