Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | APAF1 | O14727 | 1/20 | 0.52 |
| ▸ | GRK2 | P25098 | 1/20 | 0.52 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.52 |
| ▸ | MIF | P14174 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6853296 | 0.76 | POLB (0.53) | POLBAPAF1GRK2APOBEC3GMIF | |
| SCHEMBL6021765 | 0.76 | POLB (0.56) | POLBAPAF1GRK2APOBEC3GMIF | |
| SCHEMBL5994924 | 0.76 | POLB (0.56) | POLBAPAF1GRK2APOBEC3GMIF | |
| SCHEMBL5994929 | 0.76 | POLB (0.56) | POLBAPAF1GRK2APOBEC3GMIF | |
| SCHEMBL5997363 | 0.73 | APAF1 (0.53) | POLBAPAF1GRK2APOBEC3GMIF | |
| SCHEMBL5995363 | 0.73 | APAF1 (0.53) | POLBAPAF1GRK2APOBEC3GMIF | |
| SCHEMBL7463485 | 0.73 | POLB (0.53) | POLBAPAF1GRK2APOBEC3GMIF | |
| SCHEMBL8941438 | 0.72 | POLB (0.50) | POLBAPAF1GRK2APOBEC3GRAB9A | |
| SCHEMBL2921731 | 0.72 | — | — | |
| SCHEMBL12518921 | 0.71 | NPC1 (0.62) | POLBAPAF1GRK2APOBEC3GMIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552424-A | Isoxazolines as antiinflammatory agents | PFIZER INC. (US) | 1996-09-03 | — | — | US | disclosed |