Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | GRK2 | P25098 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941420 | 0.88 | MIF (0.38) | POLBAPAF1GRK2APOBEC3GRAB9A | |
| SCHEMBL8941571 | 0.88 | ALOX5 (0.47) | POLBRAB9AMEN1KMT2ACYP2C19 | |
| SCHEMBL8941440 | 0.87 | HTT (0.47) | POLBAPAF1GRK2APOBEC3GNPC1 | |
| SCHEMBL8941576 | 0.83 | ALOX5 (0.48) | POLBRAB9AMEN1KMT2ACYP2C19 | |
| SCHEMBL8941414 | 0.81 | F10 (0.42) | SMN1; SMN2CYP1A2MAPTALDH1A1LMNA | |
| SCHEMBL21066152 | 0.77 | POLB (0.53) | POLBAPAF1GRK2APOBEC3GRAB9A | |
| SCHEMBL8941751 | 0.76 | ALOX5 (0.53) | RAB9AMAPK10CYP2C19NPC1CYP3A4 | |
| SCHEMBL8941462 | 0.74 | PPARG (0.44) | POLBAPAF1GRK2APOBEC3GRAB9A | |
| SCHEMBL8941375 | 0.74 | ALOX5 (0.46) | POLBAPAF1GRK2APOBEC3GRAB9A | |
| SCHEMBL8941395 | 0.72 | POLB (0.52) | POLBAPAF1GRK2APOBEC3GRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552424-A | Isoxazolines as antiinflammatory agents | PFIZER INC. (US) | 1996-09-03 | — | — | US | disclosed |