Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11032462 | 0.83 | ALDH1A1 (0.40) | ALDH1A1TET2KEAP1NFE2L2HCAR2 | |
| SCHEMBL28596124 | 0.80 | ALDH1A1 (0.34) | ALDH1A1TET2 | |
| SCHEMBL11171013 | 0.77 | ALDH1A1 (0.36) | ALDH1A1TET2 | |
| SCHEMBL11171016 | 0.77 | ALDH1A1 (0.36) | ALDH1A1TET2 | |
| SCHEMBL3246109 | 0.76 | ALDH1A1 (0.39) | ALDH1A1TET2KEAP1NFE2L2HCAR2 | |
| SCHEMBL7868945 | 0.76 | ALDH1A1 (0.39) | ALDH1A1TET2KEAP1NFE2L2HCAR2 | |
| SCHEMBL2417309 | 0.76 | ALDH1A1 (0.39) | ALDH1A1TET2KEAP1NFE2L2HCAR2 | |
| SCHEMBL71370 | 0.76 | ALDH1A1 (0.39) | ALDH1A1TET2KEAP1NFE2L2HCAR2 | |
| SCHEMBL900883 | 0.76 | ALDH1A1 (0.34) | ALDH1A1TET2 | |
| SCHEMBL1782364 | 0.74 | TSHR (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106496450-A | A kind of stress response type polymethyl methacrylate modified silicon boron polymer microgel and preparation method thereof | 深圳航天科技创新研究院 | 2017-03-15 | — | — | CN | disclosed |
| EP-0732911-A4 | OPTIONALLY CROSSLINKABLE COATINGS, COMPOSITIONS AND METHODS OF USE | MINNESOTA MINING & MFG (US) | 1996-12-30 | — | — | EP | disclosed |
| EP-0732911-A1 | OPTIONALLY CROSSLINKABLE COATINGS, COMPOSITIONS AND METHODS OF USE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-09-25 | — | — | EP | disclosed |
| WO-1995015740-A1 | OPTIONALLY CROSSLINKABLE COATINGS, COMPOSITIONS AND METHODS OF USE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-06-15 | — | — | WO | disclosed |