SCHEMBL3246109

SCHEMBL3246109

COC(=O)C(C)=CC(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
MAPT P10636 1/20 0.36
GPR35 Q9HC97 1/20 0.33
TET2 Q6N021 1/20 0.32
NOTUM Q6P988 1/20 0.32
KEAP1 Q14145 1/20 0.31
NFE2L2 Q16236 1/20 0.31
HCAR2 Q8TDS4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL71370 1.00 ALDH1A1 (0.39) ALDH1A1MAPTGPR35TET2NOTUM
SCHEMBL29101734 0.82 ALDH1A1 (0.36) ALDH1A1MAPTGPR35TET2NOTUM
SCHEMBL11032462 0.78 ALDH1A1 (0.40) ALDH1A1TET2KEAP1NFE2L2HCAR2
SCHEMBL4009654 0.78 ALDH1A1 (0.35) ALDH1A1MAPTTET2KEAP1NFE2L2
SCHEMBL2417309 0.76 ALDH1A1 (0.39) ALDH1A1MAPTGPR35TET2KEAP1
SCHEMBL11938107 0.76 ALDH1A1 (0.36) ALDH1A1MAPTGPR35TET2KEAP1
SCHEMBL8941587 0.76 ALDH1A1 (0.39) ALDH1A1TET2KEAP1NFE2L2HCAR2
SCHEMBL7868945 0.76 ALDH1A1 (0.39) ALDH1A1MAPTGPR35TET2KEAP1
SCHEMBL3230569 0.76 GLO1 (0.45) ALDH1A1MAPT
SCHEMBL8828773 0.76 GLO1 (0.45) ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114206015-A Method for manufacturing a circuit-board structure 佳胜科技股份有限公司 2022-03-18 CN disclosed
CN-113549187-A Waterborne polyurethane for microfiber leather and preparation method thereof 扬州工业职业技术学院 2021-10-26 CN disclosed
CN-112745269-A Phenyl isoxazoline compound and application thereof 沈阳中化农药化工研发有限公司 2021-05-04 CN disclosed
EP-2927718-B1 IR-CUT FILTER AND MANUFACTURING METHOD THEREOF, SOLID STATE IMAGE PICKUP DEVICE, AND LIGHT BLOCKING FILM FORMATION METHOD FUJIFILM CORP (JP) 2018-09-19 EP disclosed
US-9952361-B2 IR cut filter, method for manufacturing the same, and solid-state imaging device FUJIFILM CORPORATION (JP) 2018-04-24 US disclosed
US-9571706-B2 Support plate for solid-state imaging element, method for manufacturing the same, and solid-state imaging device FUJIFILM CORPORATION (JP) 2017-02-14 US disclosed
EP-2927959-A1 SOLID-STATE IMAGE CAPTURE ELEMENT RETAINING SUBSTRATE AND FABRICATION METHOD THEREFOR, AND SOLID-STATE IMAGE CAPTURE DEVICE FUJIFILM Corporation (JP) 2015-10-07 EP disclosed
EP-2927718-A1 IR-CUT FILTER AND MANUFACTURING METHOD THEREOF, SOLID STATE IMAGE PICKUP DEVICE, AND LIGHT BLOCKING FILM FORMATION METHOD FUJIFILM Corporation (JP) 2015-10-07 EP disclosed
US-20150264231-A1 SUPPORT PLATE FOR SOLID-STATE IMAGING ELEMENT, METHOD FOR MANUFACTURING THE SAME , AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2015-09-17 US disclosed
US-20150260886-A1 IR CUT FILTER, METHOD FOR MANUFACTURING THE SAME, AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2015-09-17 US disclosed
EP-2209791-A1 HETEROCYCLIC DERIVATIVES N.V. Organon (NL) 2010-07-28 EP disclosed
WO-2009062930-A1 HETEROCYCLIC DERIVATIVES N.V. ORGANON (NL) 2009-05-22 WO disclosed
US-20070166250-A1 COSMETIC POLYMER COMPOSITION AND COSMETIC MITSUBISHI CHEMICAL CORPORATION 2007-07-19 US disclosed
US-20040223933-A1 Cosmetic polymer composition and cosmetic MITSUBISHI CHEMICAL CORPORATION 2004-11-11 US disclosed
EP-1440680-A1 COSMETIC POLYMER COMPOSITION AND COSMETIC Mitsubishi Chemical Corporation (JP) 2004-07-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070166250-A1 COSMETIC POLYMER COMPOSITION AND COSMETIC ERCC1, PCNA, CUTA ALDH1A1 1048/4885MAPT 338/4885GPR35 962/4885
US-20040223933-A1 Cosmetic polymer composition and cosmetic PCNA, ERCC1, CUTA ALDH1A1 1133/4885MAPT 314/4885GPR35 1033/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.