Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.54 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.50 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11507063 | 0.87 | PTPRZ1 (0.61) | HTTSMN1; SMN2PTPN1PTPRZ1SOS1 | |
| SCHEMBL8941531 | 0.86 | PTPRZ1 (0.50) | HTTSMN1; SMN2PTPN1PTPRZ1SOS1 | |
| SCHEMBL6848913 | 0.85 | HTT (0.74) | HTTSMN1; SMN2SOS1HTR6LMNA | |
| SCHEMBL8941672 | 0.85 | SOS1 (0.51) | HTTSMN1; SMN2PTPN1PTPRZ1SOS1 | |
| SCHEMBL9323430 | 0.83 | HTT (0.78) | HTTSMN1; SMN2SOS1HTR6LMNA | |
| SCHEMBL8941529 | 0.82 | PTPRZ1 (0.56) | HTTSMN1; SMN2PTPN1PTPRZ1SOS1 | |
| SCHEMBL17559302 | 0.81 | HTT (0.81) | HTTSMN1; SMN2SOS1HTR6LMNA | |
| SCHEMBL146566 | 0.81 | HTT (0.81) | HTTSMN1; SMN2SOS1HTR6LMNA | |
| SCHEMBL6123058 | 0.81 | HTT (0.81) | HTTSMN1; SMN2SOS1HTR6LMNA | |
| SCHEMBL11415437 | 0.81 | HTT (0.81) | HTTSMN1; SMN2SOS1HTR6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480568-A | FOR LUBRICATING METAL CONTAINING SURFACES | THE DOW CHEMICAL COMPANY (US) | 1996-01-02 | — | — | US | claimed |