Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.49 |
| ▸ | KIF11 | P52732 | 2/20 | 0.49 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941529 | 0.93 | PTPRZ1 (0.56) | PTPRZ1KIF11SOS1HTTLMNA | |
| SCHEMBL28217808 | 0.89 | KIF11 (0.58) | PTPRZ1KIF11HTTLMNASMN1; SMN2 | |
| SCHEMBL11507063 | 0.87 | PTPRZ1 (0.61) | PTPRZ1KIF11SOS1HTTLMNA | |
| SCHEMBL8941634 | 0.86 | HTT (0.57) | PTPRZ1SOS1HTTLMNASMN1; SMN2 | |
| SCHEMBL8941672 | 0.85 | SOS1 (0.51) | PTPRZ1SOS1HTTLMNASMN1; SMN2 | |
| SCHEMBL8941500 | 0.81 | PTPRZ1 (0.51) | PTPRZ1SOS1HTTSMN1; SMN2PTPN1 | |
| SCHEMBL8941541 | 0.81 | PTPRZ1 (0.51) | PTPRZ1SOS1HTTSMN1; SMN2PTPN1 | |
| SCHEMBL9625501 | 0.80 | HTT (0.67) | BCL2L1MCL1SOS1HTTLMNA | |
| SCHEMBL8941611 | 0.79 | PTPRZ1 (0.46) | PTPRZ1SOS1HTTLMNASMN1; SMN2 | |
| SCHEMBL11060588 | 0.79 | PTPRZ1 (0.53) | PTPRZ1SOS1HTTLMNAPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480568-A | FOR LUBRICATING METAL CONTAINING SURFACES | THE DOW CHEMICAL COMPANY (US) | 1996-01-02 | — | — | US | claimed |