SCHEMBL8941672

SCHEMBL8941672

O=S(=O)(c1ccc(Oc2cccc(Oc3ccccc3)c2)cc1)C(F)(F)F

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SOS1 Q07889 1/20 0.51
PTPRZ1 P23471 1/20 0.49
PGR P06401 4/20 0.48
NR3C1 P04150 1/20 0.48
AR P10275 1/20 0.48
ESR2 Q92731 1/20 0.48
HTT P42858 3/20 0.47
LMNA P02545 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
EPAS1 Q99814 3/20 0.47
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
PTPN1 P18031 1/20 0.46
FFAR1 O14842 1/20 0.44
FFAR4 Q5NUL3 1/20 0.44
PPARG P37231 1/20 0.44
SDHB P21912 1/20 0.44
PTGES2 Q9H7Z7 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8941541 0.97 PTPRZ1 (0.51) SOS1PTPRZ1PGRNR3C1AR
SCHEMBL8941500 0.97 PTPRZ1 (0.51) SOS1PTPRZ1PGRNR3C1AR
SCHEMBL8941549 0.90 SOS1 (0.49) SOS1PGRNR3C1ARESR2
SCHEMBL6000396 0.88 PTGES (0.51) L3MBTL1
SCHEMBL8941546 0.88 NR3C1 (0.53) PTPRZ1PGRNR3C1ARESR2
SCHEMBL11507063 0.86 PTPRZ1 (0.61) SOS1PTPRZ1HTTLMNASMN1; SMN2
SCHEMBL8941634 0.85 HTT (0.57) SOS1PTPRZ1PGRNR3C1AR
SCHEMBL8941531 0.85 PTPRZ1 (0.50) SOS1PTPRZ1HTTLMNASMN1; SMN2
SCHEMBL8941611 0.84 PTPRZ1 (0.46) SOS1PTPRZ1PGRNR3C1AR
SCHEMBL8941529 0.80 PTPRZ1 (0.56) SOS1PTPRZ1HTTLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480568-A FOR LUBRICATING METAL CONTAINING SURFACES THE DOW CHEMICAL COMPANY (US) 1996-01-02 US claimed
US-5480568-A FOR LUBRICATING METAL CONTAINING SURFACES THE DOW CHEMICAL COMPANY (US) 1996-01-02 US disclosed