Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 13/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11547843 | 0.93 | HTT (0.58) | PTGS2PTGS1HTTALDH1A1LMNA | |
| SCHEMBL12708896 | 0.92 | PTGS2 (0.58) | PTGS2PTGS1HTTSMN1; SMN2 | |
| SCHEMBL20149706 | 0.92 | PTGS2 (0.58) | PTGS2PTGS1HTTSMN1; SMN2 | |
| SCHEMBL2758532 | 0.92 | PTGS2 (0.58) | PTGS2PTGS1HTTSMN1; SMN2 | |
| SCHEMBL1676176 | 0.92 | PTGS2 (0.63) | PTGS2PTGS1HTTLMNASMN1; SMN2 | |
| SCHEMBL14097069 | 0.92 | PTGS2 (0.65) | PTGS2PTGS1ALDH1A1 | |
| SCHEMBL16361390 | 0.90 | ENPP2 (0.67) | PTGS2PTGS1ENPP2 | |
| SCHEMBL9888806 | 0.87 | HTT (0.67) | PTGS2PTGS1HTTSMN1; SMN2 | |
| SCHEMBL10014119 | 0.87 | HTT (0.67) | PTGS2PTGS1HTTSMN1; SMN2 | |
| SCHEMBL15097133 | 0.87 | HTT (0.67) | PTGS2PTGS1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480568-A | FOR LUBRICATING METAL CONTAINING SURFACES | THE DOW CHEMICAL COMPANY (US) | 1996-01-02 | — | — | US | claimed |