Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 2/20 | 0.35 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941658 | 0.77 | FABP3 (0.40) | SOAT1FABP3FABP4FABP5 | |
| SCHEMBL8941282 | 0.73 | SOAT2 (0.46) | SOAT1SOAT2MYCMAP2K3RXRA | |
| SCHEMBL9059246 | 0.68 | RXRA (0.32) | SOAT1SOAT2MYCMAP2K3RXRA | |
| SCHEMBL14015388 | 0.66 | FABP4 (0.58) | SOAT1SOAT2MYCMAP2K3FABP3 | |
| SCHEMBL8941381 | 0.64 | SOAT1 (0.55) | SOAT1SOAT2MYCMAP2K3 | |
| SCHEMBL2456678 | 0.64 | FABP4 (0.50) | SOAT1SOAT2MYCMAP2K3FABP3 | |
| SCHEMBL17179591 | 0.63 | FABP4 (0.55) | SOAT1SOAT2MYCMAP2K3FABP3 | |
| SCHEMBL8495954 | 0.63 | FABP4 (0.48) | SOAT1SOAT2MYCMAP2K3FABP3 | |
| SCHEMBL6908862 | 0.63 | RXRA (0.56) | RXRAPPARGRARGRARARARB | |
| SCHEMBL4586960 | 0.63 | RXRA (0.56) | RXRAPPARGRARGRARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996019444-A1 | SULFONATE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1996-06-27 | — | — | WO | disclosed |
| US-5510379-A | USEFUL FOR TREATING HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-04-23 | — | — | US | disclosed |