SCHEMBL8941675

SCHEMBL8941675

CC(=O)Oc1ccc(C(OC(=O)C(c2ccccc2)c2ccccc2)OC(=O)C(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.50
ALDH1A1 P00352 4/20 0.47
HSP90AA1 P07900 1/20 0.47
GAA P10253 1/20 0.47
MAPT P10636 1/20 0.47
HSD17B10 Q99714 2/20 0.47
CYP3A4 P08684 2/20 0.47
LMNA P02545 2/20 0.47
KDM4E B2RXH2 1/20 0.47
ABCB11 O95342 1/20 0.47
ESR1 P03372 1/20 0.47
ADRA2A P08913 1/20 0.47
CYP2C9 P11712 1/20 0.47
TSHR P16473 1/20 0.47
PDE4A P27815 1/20 0.47
ADRA1A P35348 1/20 0.47
OPRK1 P41145 1/20 0.47
STAT6 P42226 1/20 0.47
SLC6A3 Q01959 1/20 0.47
HIF1A Q16665 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8037690 0.84 ALDH1A1 (0.63) ALDH1A1MAPTHSD17B10KLK7L3MBTL1
SCHEMBL8047739 0.83 L3MBTL1 (0.54) ALDH1A1CYP3A4LMNAKLK7L3MBTL1
SCHEMBL8047756 0.82 KMT2A (0.53) ALDH1A1GAAHSD17B10CYP3A4LMNA
SCHEMBL8853492 0.79 ESR1 (0.49) ALDH1A1GAAHSD17B10CYP3A4LMNA
SCHEMBL24747286 0.79 LMNA (0.64) ELANEALDH1A1HSP90AA1GAAMAPT
SCHEMBL28927408 0.77 ELANE (0.59) ELANEALDH1A1HSP90AA1GAAMAPT
SCHEMBL11605128 0.77 ELANE (0.59) ELANEALDH1A1HSP90AA1GAAMAPT
Diphenylacetic Acid SCHEMBL8941679 0.77 MAPT (0.53) ELANEALDH1A1HSP90AA1GAAMAPT
SCHEMBL9619689 0.75 KMT2A (0.48) ELANEALDH1A1CYP3A4LMNATSHR
SCHEMBL25392851 0.74 ELANE (0.56) ELANEALDH1A1HSP90AA1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5532106-A MICROELECTRONICS WITH POLYMERS, PHOTOACTIVE AGENTS AND DISSOLUTION INHIBITORS CORNELL RESEARCH FOUNDATION, INC. (US) 1996-07-02 US claimed
US-5585223-A RADIATION ACTIVATION; HEATING; ETCHING CORNELL RESEARCH FOUNDATION, INC. (US) 1996-12-17 US disclosed
US-5532106-A MICROELECTRONICS WITH POLYMERS, PHOTOACTIVE AGENTS AND DISSOLUTION INHIBITORS CORNELL RESEARCH FOUNDATION, INC. (US) 1996-07-02 US disclosed