Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.40 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6894684 | 0.85 | DPP4 (0.38) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL31575664 | 0.78 | DPP4 (0.33) | DPP4DPP8DPP9ALDH1A1SMN1; SMN2 | |
| SCHEMBL137918 | 0.77 | DPP4 (0.34) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL27619762 | 0.75 | SLC6A1 (0.33) | SMN1; SMN2 | |
| SCHEMBL444869 | 0.74 | DPP4 (0.42) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL30924754 | 0.73 | DPP4 (0.60) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL6371844 | 0.73 | DPP4 (0.60) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL29565533 | 0.73 | DPP4 (0.60) | DPP4DPP8DPP9FAPDPP7 | |
| Proline SCHEMBL29291632 | 0.73 | DPP4 (0.43) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL825679 | 0.73 | DPP4 (0.60) | DPP4DPP8DPP9FAPDPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543496-A | NONAPEPTIDE; ANTIINFLAMMATORY AGENTS, ANALGESICS | SCIOS NOVA INC. (US) | 1996-08-06 | — | — | US | disclosed |
| WO-1994019372-A1 | CYCLIC BRADYKININ ANTAGONIST PEPTIDES | SCIOS NOVA INC. (US) | 1994-09-01 | — | — | WO | disclosed |