Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.43 |
| ▸ | PARP1 | P09874 | 3/20 | 0.43 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8128473 | 0.84 | ALDH1A1 (0.45) | PARP10PARP1PARP4PARP2CA1 | |
| SCHEMBL11337669 | 0.77 | AR (0.43) | PARP1ALDH1A1KDM4EHSD17B10LCK | |
| SCHEMBL11512947 | 0.76 | CASP1 (0.41) | ALDH1A1LMNAHTTKDM4EHSD17B10 | |
| SCHEMBL30217617 | 0.73 | ALDH1A1 (0.76) | PARP10PARP1PARP4PARP2CA1 | |
| SCHEMBL761126 | 0.73 | ALDH1A1 (0.76) | PARP10PARP1PARP4PARP2CA1 | |
| SCHEMBL7608923 | 0.72 | KDM4E (0.62) | CA1CA2ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL6114158 | 0.72 | ALDH1A1 (0.50) | PARP10PARP1PARP4PARP2CA1 | |
| SCHEMBL1690496 | 0.72 | MAPK1 (0.55) | PARP10PARP1PARP4PARP2CA1 | |
| SCHEMBL29588341 | 0.72 | MAPK1 (0.55) | PARP10PARP1PARP4PARP2CA1 | |
| SCHEMBL14213204 | 0.72 | PARP1 (0.48) | PARP10PARP1PARP4PARP2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559216-A | AZO COUPLING | HOECHST AG (DE) | 1996-09-24 | — | — | US | disclosed |