Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | GAA | P10253 | 6/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503076 | 0.85 | CASP1 (0.43) | CASP1MAPTGAAMAPK1ALDH1A1 | |
| SCHEMBL398357 | 0.78 | CASP1 (0.48) | CASP1HSD17B10MAPTGAAMAPK1 | |
| SCHEMBL8941827 | 0.76 | PARP10 (0.43) | CASP1HSD17B10MAPTGAAMAPK1 | |
| SCHEMBL11513608 | 0.75 | CASP1 (0.38) | CASP1MAPTGAAMAPK1ALDH1A1 | |
| SCHEMBL3356943 | 0.74 | CASP1 (0.44) | CASP1HSD17B10MAPTGAAALDH1A1 | |
| SCHEMBL18403717 | 0.74 | ALDH1A1 (0.43) | CASP1HSD17B10GAAMAPK1ALDH1A1 | |
| SCHEMBL11511537 | 0.73 | ALDH1A1 (0.42) | CASP1HSD17B10MAPTGAAALDH1A1 | |
| SCHEMBL20869790 | 0.71 | CASP1 (0.41) | CASP1HSD17B10MAPTGAAMAPK1 | |
| SCHEMBL10582996 | 0.71 | MAPT (0.43) | CASP1MAPTGAAMAPK1ALDH1A1 | |
| SCHEMBL29037514 | 0.69 | CASP1 (0.40) | CASP1HSD17B10MAPTGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4171203-A | IN COMBINATION WITH A TETRAAMINOPYRIMIDING COUPLER SURFACTANTS AND THICKENERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1979-10-16 | — | — | US | disclosed |