SCHEMBL8941899

SCHEMBL8941899

NC(=O)c1ccc2c(c1N)C(=O)c1ccccc1C2=O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.76
MAPK1 P28482 7/20 0.76
MEN1 O00255 7/20 0.76
KMT2A Q03164 7/20 0.76
ALDH1A1 P00352 6/20 0.76
THRB P10828 3/20 0.76
POLB P06746 3/20 0.76
LMNA P02545 2/20 0.76
RECQL P46063 2/20 0.76
GRK6 P43250 1/20 0.64
L3MBTL1 Q9Y468 3/20 0.62
MCL1 Q07820 3/20 0.62
PKM P14618 3/20 0.62
NPSR1 Q6W5P4 2/20 0.62
KEAP1 Q14145 1/20 0.62
NFE2L2 Q16236 1/20 0.62
TDP1 Q9NUW8 1/20 0.62
MAOA P21397 3/20 0.61
MAOB P27338 1/20 0.61
SMN1; SMN2 Q16637 4/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2839419 0.86 MAPT (1.00) MAPTMAPK1MEN1KMT2AALDH1A1
Hydrochloric Acid SCHEMBL11043762 0.85 MAPT (0.97) MAPTMAPK1MEN1KMT2AALDH1A1
SCHEMBL11043758 0.85 MAPT (0.73) MAPTMAPK1MEN1KMT2AALDH1A1
SCHEMBL8744278 0.85 MAPT (0.73) MAPTMAPK1MEN1KMT2AALDH1A1
SCHEMBL10500642 0.83 KEAP1 (0.62) MAPTMAPK1MEN1KMT2AALDH1A1
SCHEMBL11014445 0.82 MAPT (0.69) MAPTMAPK1MEN1KMT2AALDH1A1
SCHEMBL8770405 0.82 MAPT (0.74) MAPTMAPK1MEN1KMT2AALDH1A1
SCHEMBL8941856 0.81 MAPT (0.71) MAPTMAPK1MEN1KMT2AALDH1A1
SCHEMBL11350345 0.81 MAPT (0.68) MAPTMAPK1MEN1KMT2AALDH1A1
SCHEMBL7121384 0.80 KEAP1 (0.86) MAPTMAPK1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed
US-5559216-A AZO COUPLING HOECHST AG (DE) 1996-09-24 US disclosed
US-5493011-A PIGMENTING HIGH MOLECULAR WEIGHT NATURAL OR SYNTHETIC ORGANIC MATERIALS HOECHST AG (DE) 1996-02-20 US disclosed
US-5026831-A Water-insoluble disazo colorants having hetero-bicyclic methylene-active compounds as coupling component HOECHST AKTIENGESELLSCHAFT (DE) 1991-06-25 US disclosed
US-4709019-A COLORFAST PIGMENTS BAYER AKTIENGESELLSCHAFT (DE) 1987-11-24 US disclosed
US-4389215-A Anthraquinone-azomethine compounds, processes for their preparation and processes for dyeing synthetic fibre materials and for pigmenting organic macromolecular substances BAYER AKTIENGESELLSCHAFT (DE) 1983-06-21 US disclosed
US-4323671-A Anthraquinone derivatives, processes for their preparation, processes for pigmenting organic macromolecular substances, and pigmented organic macromolecular material BAYER AKTIENGESELLSCHAFT (DE) 1982-04-06 US disclosed
US-4323670-A Anthraquinone-azomethine compounds, processes for their preparation and processes for pigmenting organic macromolecular substances BAYER AKTIENGESELLSCHAFT (DE) 1982-04-06 US disclosed
US-4319025-A Anthraquinone-azomethine compounds, processes for their preparation and processes for dyeing synthetic fibre materials and for pigmenting organic macromolecular substances BAYER AKTIENGESELLSCHAFT (DE) 1982-03-09 US disclosed
US-4309221-A ORGANIC PIGMENTS FOR MACROMOLECULAR SUBSTANCES;GOOD FASTNESS AND HEAT RESISTANCE BAYER AKTIENGESELLSCHAFT (DE) 1982-01-05 US disclosed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US disclosed
US-4284411-A CONDENSATION, PIGMENTING BAYER AKTIENGESELLSCHAFT (DE) 1981-08-18 US disclosed
US-4260540-A SPIN DYEING POLYACRYLONITRILE BAYER AKTIENGESELLSCHAFT (DE) 1981-04-07 US disclosed
US-4246401-A Axomethine pigments BAYER AKTIENGESELLSCHAFT (DE) 1981-01-20 US disclosed
US-4225489-A Heterocyclic azo dyes and pigments containing 4-quinazolinone moieties BAYER AKTIENGESELLSCHAFT (DE) 1980-09-30 US disclosed
US-3906012-A Production of 1-aminoanthraquinone-2-carboxamides BASF AG 1975-09-16 US disclosed