Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | EDNRA | P25101 | 1/20 | 0.52 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942036 | 0.89 | LMNA (0.48) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL8942010 | 0.88 | KDM4E (0.41) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL8941908 | 0.85 | KDM4E (0.37) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL8942056 | 0.85 | KDM4E (0.37) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL9776017 | 0.85 | KDM4E (0.61) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL8942245 | 0.85 | DPP4 (0.49) | LMNAKDM4EHSD17B10ALDH1A1ABCC4 | |
| SCHEMBL9775882 | 0.84 | LMNA (0.70) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL8942170 | 0.84 | LMNA (0.50) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL8942023 | 0.83 | LMNA (0.51) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL9142705 | 0.83 | LMNA (0.70) | LMNACYP2C9ATP6V1B2TBXA2REDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556861-A | 1,8 benzonaphthyridine derivatives and antimicrobial compositions | LABORATOIRE ROGER BELLON (FR) | 1996-09-17 | — | — | US | disclosed |