Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.37 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 6/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.35 |
| ▸ | FLT4 | P35916 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942189 | 0.88 | HPGD (0.38) | KDM4EKCNH2CYP2C9LMNAATP6V1B2 | |
| SCHEMBL8941908 | 0.88 | KDM4E (0.37) | KDM4EKCNH2CYP2C9LMNAATP6V1B2 | |
| SCHEMBL8942056 | 0.88 | KDM4E (0.37) | KDM4EKCNH2CYP2C9LMNAATP6V1B2 | |
| SCHEMBL8941894 | 0.88 | LMNA (0.52) | KDM4EKCNH2CYP2C9LMNAATP6V1B2 | |
| SCHEMBL8942245 | 0.87 | DPP4 (0.49) | KDM4EKCNH2LMNAHSD17B10ALDH1A1 | |
| SCHEMBL9527325 | 0.85 | KDM4E (0.57) | KDM4ECYP2C9LMNAATP6V1B2TBXA2R | |
| SCHEMBL9786232 | 0.84 | KDM4E (0.48) | KDM4ECYP2C9LMNAATP6V1B2TBXA2R | |
| SCHEMBL9775884 | 0.83 | LMNA (0.52) | KDM4ECYP2C9LMNAATP6V1B2TBXA2R | |
| SCHEMBL8941910 | 0.82 | KDM4E (0.40) | KDM4EKCNH2CYP2C9LMNAATP6V1B2 | |
| SCHEMBL8941958 | 0.82 | ALDH1A1 (0.39) | KDM4EKCNH2CYP2C9LMNAATP6V1B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556861-A | 1,8 benzonaphthyridine derivatives and antimicrobial compositions | LABORATOIRE ROGER BELLON (FR) | 1996-09-17 | — | — | US | disclosed |