Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.55 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.55 |
| ▸ | EDNRA | P25101 | 1/20 | 0.55 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | HPGD | P15428 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9775882 | 0.90 | LMNA (0.70) | KDM4EDRD3LMNACYP2C9ATP6V1B2 | |
| SCHEMBL9775896 | 0.89 | ALDH1A1 (0.49) | KDM4EDRD3LMNACYP2C9ATP6V1B2 | |
| SCHEMBL9527325 | 0.88 | KDM4E (0.57) | KDM4EDRD3LMNACYP2C9ATP6V1B2 | |
| SCHEMBL9775918 | 0.87 | LMNA (0.66) | KDM4EDRD3LMNACYP2C9ATP6V1B2 | |
| SCHEMBL8941894 | 0.85 | LMNA (0.52) | KDM4EDRD3LMNACYP2C9ATP6V1B2 | |
| SCHEMBL8942023 | 0.84 | LMNA (0.51) | KDM4EDRD3LMNACYP2C9ATP6V1B2 | |
| SCHEMBL9775873 | 0.84 | KDM4E (0.52) | KDM4ELMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL8942170 | 0.84 | LMNA (0.50) | KDM4EDRD3LMNACYP2C9ATP6V1B2 | |
| SCHEMBL8942063 | 0.84 | LMNA (0.50) | KDM4EDRD3LMNACYP2C9ATP6V1B2 | |
| SCHEMBL8942156 | 0.84 | LMNA (0.50) | KDM4EDRD3LMNACYP2C9ATP6V1B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5004745-A | Benzo[1,8]naphthyridine derivatives, their preparation and the compositions which contain them | LABORATOIRE ROGER BELLON (FR) | 1991-04-02 | — | — | US | disclosed |