Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3715267 | 0.85 | MAPT (0.53) | ALDH1A1MAPTKDM4ESLC6A2SLC6A4 | |
| SCHEMBL10651794 | 0.82 | PDE7A (0.51) | ALDH1A1KMT2ASMN1; SMN2PDE7ATSHR | |
| SCHEMBL11202237 | 0.81 | PDE7A (0.49) | ALDH1A1MAPTKDM4ESLC6A2SLC6A4 | |
| SCHEMBL30886771 | 0.81 | PDE7A (0.51) | ALDH1A1MAPTKDM4ESLC6A2SLC6A4 | |
| SCHEMBL2593514 | 0.81 | PDE7A (0.51) | ALDH1A1MAPTKDM4ESLC6A2SLC6A4 | |
| SCHEMBL13603779 | 0.80 | RXFP1 (0.54) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10651245 | 0.80 | ALDH1A1 (0.56) | ALDH1A1MAPTPDE7AHTT | |
| SCHEMBL10652731 | 0.79 | ALDH1A1 (0.55) | ALDH1A1PDE7ATSHR | |
| SCHEMBL9850838 | 0.79 | LMNA (0.47) | ALDH1A1MEN1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL11303911 | 0.78 | MAPT (0.52) | ALDH1A1MAPTKDM4ESLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514589-A | ACYLATION OF COMPOUND IN THE PRESENCE OF LIPASE IMMOBILIZED ON SUPPORT OF SACCHAROSE | ORION-YHTYMA OY FERMION (FI) | 1996-05-07 | — | — | US | disclosed |
| EP-0617130-A2 | Method for the resolution of racemic mixtures | ORION-YHTYMÄ OY FERMION (FI) | 1994-09-28 | — | — | EP | disclosed |
| US-4155905-A | 6-Substituted penicillanic acid and derivatives thereof | E. R. SQUIBB & SONS, INC. (US) | 1979-05-22 | — | — | US | disclosed |
| US-4077967-A | 6-Substituted penicillanic acid and derivatives thereof | E. R. SQUIBB & SONS, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4061629-A | 6-Amino-6-arylthio penicillanic acids and derivatives thereof | E. R. SQUIBB & SONS, INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4061851-A | 7-Amino-7-arylthio cephalosporins | E. R. SQUIBB & SONS, INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4029669-A | 6-Benzalimino-6-arylthio penicillanic acids and derivatives thereof | E. R. SQUIBB & SONS, INC. (US) | 1977-06-14 | — | — | US | disclosed |
| US-4026886-A | 7-Acyl-7-arylthiocephalosporins | E. R. SQUIBB & SONS, INC. (US) | 1977-05-31 | — | — | US | disclosed |
| US-3965093-A | 6-Arylthio penicillanic acid and derivatives thereof | E. R. SQUIBB & SONS, INC. (US) | 1976-06-22 | — | — | US | disclosed |
| US-3954744-A | ANTIBACTERIAL | E. R. SQUIBB & SONS, INC. (US) | 1976-05-04 | — | — | US | disclosed |