Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | STAT3 | P40763 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9775895 | 0.92 | KMT2A (0.40) | KMT2AALDH1A1TSHRSTAT3MEN1 | |
| SCHEMBL9775866 | 0.86 | STAT3 (0.43) | KMT2AALDH1A1TSHRSTAT3MEN1 | |
| SCHEMBL7234823 | 0.86 | KMT2A (0.47) | KMT2AALDH1A1TSHRSTAT3MEN1 | |
| SCHEMBL8941946 | 0.85 | ALDH1A1 (0.55) | KMT2AALDH1A1TSHRMEN1HTT | |
| SCHEMBL8942074 | 0.84 | KMT2A (0.46) | KMT2AALDH1A1TSHRSTAT3MEN1 | |
| SCHEMBL501306 | 0.84 | KMT2A (0.46) | KMT2AALDH1A1TSHRSTAT3HTT | |
| SCHEMBL9786163 | 0.83 | KMT2A (0.50) | KMT2AALDH1A1TSHRSTAT3MEN1 | |
| SCHEMBL2093801 | 0.82 | KMT2A (0.44) | KMT2AALDH1A1TSHRSTAT3MEN1 | |
| SCHEMBL10390918 | 0.82 | BAZ2B (0.42) | KMT2AALDH1A1TSHRSTAT3KDM4E | |
| SCHEMBL8942147 | 0.81 | ALDH1A1 (0.40) | KMT2AALDH1A1TSHRSTAT3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556861-A | 1,8 benzonaphthyridine derivatives and antimicrobial compositions | LABORATOIRE ROGER BELLON (FR) | 1996-09-17 | — | — | US | disclosed |