Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9775959 | 0.92 | ALDH1A1 (0.52) | ALDH1A1TSHRKMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL9786163 | 0.91 | KMT2A (0.50) | ALDH1A1TSHRKMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL7234823 | 0.88 | KMT2A (0.47) | ALDH1A1TSHRKMT2AMAPK1MAPT | |
| SCHEMBL8942028 | 0.86 | LMNA (0.59) | ALDH1A1TSHRKMT2AMAPK1LMNA | |
| SCHEMBL8942074 | 0.86 | KMT2A (0.46) | ALDH1A1TSHRKMT2AMAPK1MAPT | |
| SCHEMBL9775932 | 0.86 | ALDH1A1 (0.54) | ALDH1A1TSHRKMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL8942039 | 0.86 | ALDH1A1 (0.51) | ALDH1A1TSHRKMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL8941932 | 0.85 | KMT2A (0.45) | ALDH1A1TSHRKMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL9775880 | 0.83 | KMT2A (0.45) | ALDH1A1TSHRKMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL8942125 | 0.83 | ALDH1A1 (0.51) | ALDH1A1TSHRKMT2AMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556861-A | 1,8 benzonaphthyridine derivatives and antimicrobial compositions | LABORATOIRE ROGER BELLON (FR) | 1996-09-17 | — | — | US | disclosed |
| US-5484921-A | Process for preparing benzo[b]naphthyridines | LABORATOIRE ROGER BELLON (FR) | 1996-01-16 | — | — | US | disclosed |
| US-5442070-A | Derivatives of fluoro-quinoline carboxylic-3-acid and preparation therefor | LABORATOIRE ROGER BELLON (FR) | 1995-08-15 | — | — | US | disclosed |
| US-5053509-A | Microbiocides; AIDS | LABORATOIRE ROGER BELLON (FR) | 1991-10-01 | — | — | US | disclosed |
| US-4990515-A | Chemical intermediates | RHONE-POULENC SANTE (FR) | 1991-02-05 | — | — | US | disclosed |
| US-4970213-A | Benzo(1,8)naphthyridine derivatives as intermediates | RHONE-POULENC SANTE (FR) | 1990-11-13 | — | — | US | disclosed |