Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | TOP2A | P11388 | 3/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941969 | 0.88 | DPP4 (0.48) | DPP4KDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL8941927 | 0.87 | EPHA2 (0.38) | DPP4KDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL8942264 | 0.85 | KDM4E (0.49) | DPP4KDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL8942108 | 0.85 | KDM4E (0.37) | DPP4KDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL8941896 | 0.85 | LMNA (0.49) | KDM4EALDH1A1LMNAHSD17B10HPGD | |
| SCHEMBL8942026 | 0.85 | ALDH1A1 (0.44) | DPP4KDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL8942182 | 0.85 | EPHA2 (0.37) | DPP4KDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL8941911 | 0.84 | KDM4E (0.47) | DPP4KDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL8941888 | 0.84 | DPP4 (0.53) | DPP4KDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL8942340 | 0.83 | DPP4 (0.54) | DPP4KDM4EALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556861-A | 1,8 benzonaphthyridine derivatives and antimicrobial compositions | LABORATOIRE ROGER BELLON (FR) | 1996-09-17 | — | — | US | disclosed |