Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TOP2A | P11388 | 3/20 | 0.48 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941960 | 0.89 | DPP4 (0.49) | DPP4ALDH1A1CHRM2KDM4ELMNA | |
| SCHEMBL8942140 | 0.88 | DPP4 (0.48) | DPP4ALDH1A1CHRM2KDM4ELMNA | |
| SCHEMBL8941991 | 0.88 | DPP4 (0.48) | DPP4ALDH1A1CHRM2KDM4ELMNA | |
| SCHEMBL8941959 | 0.87 | ADRB2 (0.43) | DPP4ALDH1A1CHRM2POLBCHRM1 | |
| SCHEMBL8942094 | 0.87 | DPP4 (0.48) | DPP4ALDH1A1CHRM2POLBCHRM1 | |
| SCHEMBL8942000 | 0.86 | KMT2A (0.48) | DPP4ALDH1A1CHRM2POLBCHRM1 | |
| SCHEMBL8941969 | 0.86 | DPP4 (0.48) | DPP4ALDH1A1CHRM2KDM4ELMNA | |
| SCHEMBL9526209 | 0.86 | KDM4E (0.68) | DPP4ALDH1A1CHRM2POLBKDM4E | |
| SCHEMBL9775862 | 0.86 | ALDH1A1 (0.55) | DPP4ALDH1A1CHRM2KMT2AKDM4E | |
| SCHEMBL8942120 | 0.86 | DPP4 (0.53) | DPP4ALDH1A1CHRM2POLBCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556861-A | 1,8 benzonaphthyridine derivatives and antimicrobial compositions | LABORATOIRE ROGER BELLON (FR) | 1996-09-17 | — | — | US | claimed |
| US-5556861-A | 1,8 benzonaphthyridine derivatives and antimicrobial compositions | LABORATOIRE ROGER BELLON (FR) | 1996-09-17 | — | — | US | disclosed |