Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13233728 | 0.91 | HTR2A (0.52) | HTR2AOPRM1PNMT | |
| SCHEMBL10561985 | 0.82 | HTR2A (0.59) | HTR2AOPRM1PNMT | |
| SCHEMBL3011749 | 0.79 | HTR2A (0.50) | HTR2AOPRM1 | |
| SCHEMBL5672694 | 0.76 | OPRM1 (0.61) | HTR2AOPRM1PNMT | |
| SCHEMBL57461 | 0.76 | PNMT (0.54) | PNMT | |
| SCHEMBL24481549 | 0.74 | HTR2A (0.67) | HTR2AOPRM1 | |
| Hydrochloric Acid SCHEMBL665781 | 0.74 | PNMT (0.52) | PNMT | |
| SCHEMBL11360698 | 0.73 | MAOA (0.39) | — | |
| SCHEMBL7356520 | 0.72 | PNMT (0.44) | PNMT | |
| SCHEMBL42115 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116806217-A | Substituted cyclic modulators of protein phosphatase 2A (PP 2A) and methods of use thereof | 拉帕塔疗法公司 | 2023-09-26 | — | — | CN | disclosed |
| US-5556861-A | 1,8 benzonaphthyridine derivatives and antimicrobial compositions | LABORATOIRE ROGER BELLON (FR) | 1996-09-17 | — | — | US | disclosed |